The CT manifestations of melanoma vary depending on the location of the tumor. Generally, melanomas that occur on the skin can appear on CT scans as mass-like lesions, and the scans can show whether there are any urgent conditions involving the surrounding nerves, blood vessels, and tissues. Some patients may only show CT imaging changes such as localized thickening of the skin. In melanomas that occur inside the skull or in the vulva, the CT mainly shows localized mass-like lesions. These lesions are typically low-density foci with poor blood supply around them, and they generally have an irregular shape.