What are some good methods for treating widespread metastasis of melanoma?

Written by Sun Ming Yue
Medical Oncology
Updated on September 11, 2024
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Melanoma greatly torments patients, affecting their physical and mental health, and also unnecessarily harming their external appearance. However, treatment of this disease must be approached with caution. Surgical excision is recommended and is the first choice for the surgical treatment of melanoma. If diagnosed, surgery should be carried out promptly. The extent of excision depends on the type and location of the tumor. After excision, the resulting tissue defect is generally repaired using simple methods initially, followed by reconstructive surgery after confirming no recurrence.

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Written by Cui Fang Bo
Oncology
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Can melanoma without metastasis avoid chemotherapy?

For patients with melanoma that has not metastasized, direct surgical removal can be performed, and chemotherapy is not necessary after surgery. Melanoma is a malignant tumor that originates from melanocytes and can occur in many parts of the body, with melanomas of the skin and mucous membranes being the most common, accounting for about 70% of all cases. Once melanoma is diagnosed, if there is no distant metastasis to other organs, curative surgical removal can be performed. Postoperative treatment mainly involves immunotherapy, not systemic chemotherapy. For patients who are diagnosed with distant organ metastasis, systemic chemotherapy and immunotherapy are required.

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Written by Cui Fang Bo
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Melanoma originates from which tissue?

Melanoma does not originate from any specific tissue, but from melanocytes. Therefore, melanoma can occur in any tissue where melanocytes are present. The most common sites for melanoma are the skin and mucous membranes. Additionally, because melanocytes are widely present throughout the body, melanoma can also occur in hollow organs such as the gastrointestinal tract, in skeletal muscles, and in the nervous system. Once diagnosed, melanoma needs to be treated promptly. The main treatments include surgery, radiation therapy, chemotherapy, targeted therapy, and immunotherapy.

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Written by Cui Fang Bo
Oncology
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The significance of melanoma genetic testing

The significance of genetic testing for melanoma patients mainly involves two aspects: first, the identification of specific driver gene mutations to guide the application of targeted drugs; second, the detection of mutations in some common genes to judge the prognosis of the disease. Regarding the target gene mutations for drug selection, the commonly used ones include mutations in C-KIT, BRAF, and M-TOR. If mutations in these target genes are found, corresponding targeted drugs can be used for treatment. These drugs are generally orally administered, have relatively good efficacy, low side effects, and are suitable for the treatment of melanoma. Additionally, some genetic tests can predict the prognosis of melanoma patients based on the presence or absence of mutations.

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Written by Zhu Rui
Oncology
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Is melanoma easy to get?

Melanoma is not easy to contract, with relatively low incidence and mortality rates. Melanoma is a tumor derived from the malignant transformation of melanocytes, highly malignant, often occurring in the skin but also in mucous membranes, the choroid of the eye, the pia mater, and other various parts and tissues. In the Chinese population, it commonly appears on the extremities of the skin, such as the sole of the foot, toes, fingertips, and under the nails. According to global cancer statistics from last year, melanoma accounts for 1.6% of all new cancer cases. In China, the incidence and mortality rates of cutaneous melanoma are relatively low, with about one case per 300,000 people. In recent years, there has been a rapid increase in the incidence of melanoma, which needs to be monitored carefully.

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Written by Sun Ming Yue
Medical Oncology
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Can melanoma be detected by ultrasound?

Melanoma is a very serious disease, and if detected in its early stages, treatment should be sought promptly. If treatment is delayed, the effects of treating the disease in its advanced stages are not very good or significant. Melanoma is a type of malignant tumor that is prone to occurrence and poses a significant risk, endangering life. Generally, if melanoma is being tested, the Vacca double PAP immunoenzymatic marking method is used for detection.