Does osteosarcoma spread through blood?

Written by Guan Jing Tao
Orthopedics
Updated on December 05, 2024
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As far as we know, osteosarcoma is not transmitted through blood or infectious. If osteosarcoma had such infectious characteristics, it would be transmitted in the same way as AIDS or other sexually transmitted diseases and would be classified as a contagious disease. However, there has been no notification or relevant guidelines to date indicating that osteosarcoma can be transmitted through blood. Therefore, normal contact with patients with osteosarcoma, or caring for patients with osteosarcoma, including sharing the same food or coming into contact with their blood, generally does not lead to the transmission or contraction of osteosarcoma.

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Written by Na Hong Wei
Orthopedics
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Symptoms of osteosarcoma

The common symptoms of osteosarcoma include, first, pain which is often persistent, typically occurring at the distal femur, proximal tibia, and proximal humerus. The characteristic of this pain is that it worsens at night, more severe than during the day. Second, there is local swelling usually near joints, particularly at the three aforementioned common sites. The skin over the swelling often becomes warm and may even show redness, and some patients may have dilated surface veins. The swelling can frequently cause dysfunction of nearby joints, or restricted function. Third, systemic symptoms primarily include a persistent wasting syndrome, known as cachexia. Fourth, osteosarcomas can weaken the bone's load-bearing capacity and strength following cortical bone involvement, eventually leading to pathological fractures. Therefore, the main symptoms of osteosarcoma are localized pain, local swellings, systemic manifestations of cachexia, or pathological fractures.

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Written by Guan Jing Tao
Orthopedics
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How to alleviate the pain of osteosarcoma?

Pain in osteosarcoma patients is mostly caused by the cancer invading local bone tissue and other tissues, leading to pain, tenderness, and even sleeplessness. Therefore, the pain management follows a certain hierarchy, starting with non-steroidal anti-inflammatory drugs, followed by weak opioids, and finally strong opioids such as morphine. However, this only alleviates the pain and does not help with treatment. For early-stage osteosarcoma patients, pain management primarily involves surgery when necessary. For advanced-stage patients, it involves gradually increasing the dose of effective pain-relief medications to alleviate temporary pain. (Controlled drugs must be strictly used under the supervision of relevant physicians.)

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Written by Cheng Bin
Orthopedics
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Is osteosarcoma highly malignant?

First of all, it is certain that osteosarcoma is very malignant. Once osteosarcoma is detected, it is necessary to actively prepare for surgery, rule out surgical contraindications, and then proceed with surgical treatment. During the surgery, efforts should be made to perform an extended resection, and if necessary, amputation may be required. After the surgery, the excised specimen must be sent for pathological examination to determine the pathological type. Then, based on the examination results, effective radiotherapy and chemotherapy should be chosen to control the possibility of recurrence or metastasis of osteosarcoma and to extend the patient's life as much as possible.

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Written by Guan Jing Tao
Orthopedics
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Can hot compresses relieve pain for osteosarcoma?

Osteosarcoma has very limited pain relief effects through simple or pure hot compresses. As the lesion progresses, hot compresses can become completely ineffective or have very unclear effects. Clinical manifestations include pain and swelling, with local formation of lumps or tumor-like appearances. It can also affect the joint mobility around it, and even cause atrophy of limbs and muscles. In terms of treatment, it still relies on early surgical excision, but the prognosis is still not very optimistic.

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Written by Na Hong Wei
Orthopedics
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Is osteosarcoma sensitive to chemotherapy?

Osteosarcoma is relatively sensitive to chemotherapy. Currently, the treatment of malignant tumors is primarily a comprehensive approach centered around surgery. However, the treatment of osteosarcoma should start with neoadjuvant chemotherapy, which involves administering a certain number of chemotherapy sessions, generally around six, before surgery. After chemotherapy, the tumor itself shrinks in size, pain is reduced, and the patient's cachexia also improves. At this point, choosing an optimal surgical method based on the tumor’s location and size becomes feasible, whether it involves amputation, limb-salvage, or other treatment methods such as the implantation of prosthetics. Postoperative chemotherapy is then administered. With this approach, there is a significant improvement in the five-year survival rate. Therefore, the treatment of osteosarcoma is inseparable from chemotherapy, requiring both preoperative and postoperative chemotherapy, making osteosarcoma quite sensitive to chemotherapy overall.