Osteosarcoma, also known as osteogenic sarcoma, is a primary malignant tumor of the bone. It ranks second in incidence among bone tumors and has a relatively high incidence and malignancy rate. It is more common in adolescents and occurs more frequently in males than in females. The earliest clinical symptoms of this disease include dull pain and persistent pain that worsens with activity, as well as nighttime pain, which is more pronounced than daytime pain. This is a very important characteristic, indicating that patients experience nighttime pain and rest pain. The affected area may develop a rapidly growing mass that changes significantly in size from month to month. If the tumor grows large, pressing on it can cause pain, but in the early stages when the tumor is not very large, the tenderness may not be very apparent, presenting only as localized spontaneous pain, which requires attention.