Osteosarcoma is malignant.

Written by Cheng Bin
Orthopedics
Updated on September 18, 2024
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Regarding whether osteosarcoma is benign or malignant, it is certain that osteosarcoma is a malignant tumor with a very high degree of malignancy. Once osteosarcoma is definitively diagnosed, aggressive treatment is necessary. Surgery is the main treatment approach, aiming to perform as extensive a resection as possible, or amputation may be required when necessary. After surgery, the resected specimen must be sent for pathological examination. Based on the type of pathology, the next step in treatment, either radiotherapy or chemotherapy, will be determined to minimize the recurrence of osteosarcoma, as a recurrence can endanger the patient's life.

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Written by Wang Cheng Lin
Orthopedics
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Do benign osteosarcomas use chemotherapy?

First of all, all osteosarcomas are malignant; osteosarcoma is a type of malignant tumor with no benign variant. Regarding the treatment of osteosarcoma, the first step is chemotherapy. After confirming the diagnosis through pathological examination and confirming it is osteosarcoma, The first step is chemotherapy, which can stabilize the tumor cells; Then, the main tissue is surgically removed, as well as the surrounding infiltrated soft tissue; The third step is to use chemotherapy again to eliminate the residual cancer cells. This treatment protocol of chemotherapy-surgery-chemotherapy is currently the most common and advanced method in the country. It can significantly improve the patient's survival rate, reduce the risk of amputation, and can also prevent the recurrence of osteosarcoma.

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Written by Na Hong Wei
Orthopedics
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Can osteosarcoma be felt?

Osteosarcoma can be felt by touch, and its main clinical manifestations include persistent progressive pain, which intensifies at night. Secondly, there are local lumps, commonly located at the distal femur, proximal tibia, and proximal humerus, which are high incidence areas for osteosarcoma. In such cases, you don't even need to touch it; you can see it with the naked eye because the swelling is quite severe. Additionally, the surrounding skin may appear reddened and warm, and superficial veins may become prominently swollen, indicating that the skin over the affected area looks different from normal skin. Moreover, in the area affected by osteosarcoma, the bone may show a spindle-shaped enlargement, looking like a spindle-shaped lump, causing the joint area and the surrounding normal joints to be clearly abnormal. Therefore, in cases of obvious symptoms of osteosarcoma, not only can you see the tumor, but you can also feel it. However, patients often will not let you touch it, as touching can cause pain and even force the joint and surrounding muscles into a forced state. This forced condition helps alleviate pain in the joint and surrounding areas. Thus, osteosarcoma can indeed be felt by touch.

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Written by Guan Yu Hua
Orthopedic Surgery
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Characteristics of Osteosarcoma

Osteosarcoma is a malignant tumor of the bone that primarily occurs in adolescents and young adults, commonly found at the metaphyseal ends of long bones. For example, it may occur at the distal end of the tibia, the distal end of the femur, or the metaphyseal end of the humerus. Clinically, the main symptom is pain, which is persistent and more noticeable at night, accompanied by a local mass, limited movement, increased local skin temperature, distended veins, and general symptoms such as weight loss and even cachexia. Some patients may experience pathological fractures. Often, there are no symptoms in the early stages, and by the time it is detected, it is usually in an intermediate or advanced stage. Radiographic examination typically shows a Codman's triangle or sunburst pattern. Early detection and treatment are crucial. The usual treatment choice is surgical, such as deactivation and reimplantation, or limb-salvage surgery with prosthetic implantation. Additionally, amputation followed by extensive chemotherapy is another option. With recent advances in chemotherapy, there has been significant improvement in life extension.

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Written by Wang Cheng Lin
Orthopedics
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What are the symptoms of osteosarcoma?

Symptoms of Osteosarcoma: The first is pain at the site of occurrence. This pain may be intermittent and not very pronounced in the early stages. As the condition progresses, the severity of the pain gradually increases, transitioning from intermittent to persistent pain; The second is the formation of a lump. You can feel a lump on the limb with your hand, and this lump is clearly tender to the touch; The third is limping, which is mainly caused by the pain in the limb; The fourth is the most common systemic symptoms. Patients with this malignant tumor will exhibit fever, weight loss, anemia, and pathological fractures. These are the main symptoms of osteosarcoma currently observed in clinical settings.

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Written by Na Hong Wei
Orthopedics
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Is osteosarcoma a cancer?

If we are to speak strictly, osteosarcoma is not cancer. This is because cancer typically refers to malignant tumors of epithelial tissue, whereas osteosarcoma, like all sarcomas, is a malignant tumor that occurs in connective or muscle tissue. Therefore, their origins are different: osteosarcoma is not cancer; it is a malignant tumor that occurs in bone tissue, commonly found in the distal femur, proximal tibia, and proximal humerus. So, strictly speaking, osteosarcoma is a sarcoma, a malignant tumor that occurs in bone tissue. It is not what one would typically refer to as cancer, which usually pertains to epithelial tissues, such as in cases of skin cancer or breast cancer. Osteosarcoma is therefore classified as a sarcoma, not as cancer.