Is tertiary syphilis highly contagious?

Written by Zhu Zhu
Dermatology
Updated on December 06, 2024
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The infectivity of tertiary syphilis is not very high, although it still possesses relatively weak contagiousness. Syphilis in its primary and secondary stages often shows high titers in tests and has stronger infectivity, while tertiary syphilis has reduced infectivity. However, tertiary syphilis can easily lead to various complications, including damage to tissues and organs, making it more harmful than the primary and secondary stages. Therefore, it is crucial to treat tertiary syphilis promptly.

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Written by Luo Hong
Dermatology Department
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Gonorrhea and syphilis symptoms

Gonorrhea infection, if in males, generally presents with significant urethral irritation including symptoms such as urethral discharge, frequent urination, urgent urination, and pain during urination. However, in females with gonorrhea, it may cause increased vaginal discharge and an unusual odor, but many women with gonorrhea do not exhibit any symptoms. As for syphilis, if it is primary syphilis, ulcers may appear on the genitals, lips, or other body parts, known as chancres. In typical secondary syphilis, pinkish-red rashes may appear on the palms of the hands and soles of the feet, usually without itching, although rashes may also occur on the trunk and might not be itchy. Additionally, many cases of syphilis remain latent and show no clear symptoms.

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Written by Luo Hong
Dermatology Department
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Can syphilis be completely cured?

Syphilis can generally be completely cured nowadays, except neurosyphilis which is somewhat harder to treat, as ordinary syphilis is curable and neurosyphilis may relapse occasionally. However, most current cases of syphilis fall into categories of latent, primary, or secondary syphilis. Tertiary syphilis is less common, and forms such as neurosyphilis and osteal syphilis belong to this stage. Therefore, when treated at a regular hospital with a standard treatment regimen, primarily using penicillin, administered as a long-acting intramuscular injection once a week, the recommended course of treatment usually consists of three to four weeks. If there is an allergy to penicillin, doxycycline can be used as an oral substitute for half a month.

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Written by Zhu Zhu
Dermatology
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How long does tertiary syphilis appear?

Tertiary syphilis often appears two to three years after contracting syphilis. Syphilis is staged based on the time of onset, and is typically divided into primary, secondary, and tertiary stages. Tertiary syphilis is the latest and most severe stage among these, often affecting the heart, nervous system, skin, and other areas. Due to the risk of severe complications, early and timely treatment is recommended to prevent the occurrence of tertiary syphilis.

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Written by Zhu Zhu
Dermatology
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Does third-stage syphilis rash itch?

People with tertiary syphilis generally do not experience itching. Tertiary syphilis represents the later stages of the disease manifestation. Typically, the symptoms on the skin are neither painful nor itchy, which is the case for most individuals. However, some patients may feel differently from the majority, experiencing anomalies, or they might develop secondary conditions such as eczema or allergies, among others, possibly leading to mild itching and so on.

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Written by Luo Hong
Dermatology Department
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Can syphilis antibodies be detected during the hard chancre stage?

During the hard chancre phase of syphilis, a portion of cases can test positive for Treponema pallidum, although some tests may return negative results. In such cases, it is advisable to retest after one month. The earliest detectable antibodies for Treponema pallidum are usually of two types: a Treponema pallidum-specific antibody, which appears earlier than the non-specific antibodies. There are tests for non-specific antibodies, commonly referred to as RPR or TRUST, which are standard practices in major hospitals. Therefore, in early-stage syphilis or primary syphilis with hard chancre, it is possible to find Treponema pallidum-specific antibodies positive, RPR or TRUST negative, or both negative. If syphilis is strongly suspected in such cases, a retest is recommended after one month.