Polycystic kidney disease is an autosomal dominant hereditary disease. As the patient's age increases, the cysts of polycystic kidney will gradually enlarge, and the risk of renal function abnormalities and related complications will increase. If the patient catches a cold, it will exacerbate the abnormality of kidney function. Furthermore, the use of some antiviral and antibacterial drugs metabolized through the kidneys can also increase the burden on the kidneys, further causing damage to them. Therefore, patients with polycystic kidney disease should try to avoid colds, diarrhea, urinary tract infections, and other related infectious diseases.