Once keloids appear, they are essentially irreversible, meaning that they cannot be completely cured clinically. The formation of keloids is mostly related to one's own constitution, such as a keloid-prone skin type.

Some keloids are also due to trauma occurring in areas of the skin where muscular tension is relatively high, or where the wound is indeed large and deep, which might lead to the formation of keloids. In such cases, localized drug injections can be used to reduce and soften the keloids.

One can also use ointments that soften scars, such as keloid soothing and softening cream, but these require long-term application to be effective. If the keloid is relatively small, cosmetic surgery to remove and re-sew the area can also be an option for treatment.

In summary, once keloids have developed, they are not easy to completely cure.