Pertussis prone age group

Written by Yan Xin Liang
Pediatrics
Updated on April 01, 2025
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Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by Bordetella pertussis. The main age group affected by this disease are infants and young children, with the highest susceptibility seen in children under five years old, particularly infants younger than one year. The incidence of this disease has significantly decreased due to the widespread implementation of pertussis vaccination. Clinically, the disease is characterized by a cough that gradually worsens, presenting as typical paroxysmal, frequent coughing, and frothy sputum, with a crowing echo in the cough. The course of the disease can last up to three months.

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Written by Li Jian Wu
Pulmonology
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Treatment methods for pertussis in children

The treatment methods for pertussis in children mainly involve anti-inflammatory processes, along with etiological treatment. Pertussis in children typically requires the selection of antimicrobial drugs to eradicate Bordetella pertussis. Clinically, macrolide antibiotics are primarily chosen, such as erythromycin, azithromycin, or clarithromycin. Also, depending on the nature of the cough, some central antitussive agents or cough and phlegm relieving drugs can be used to alleviate the symptoms of cough. Additionally, in the acute phase of inflammation where fever is present, antipyretic analgesics should be taken for symptomatic treatment. (Medication use should be under the guidance of a doctor.)

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Written by Li Jian Wu
Pulmonology
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Whooping cough vaccine at what age?

The pertussis vaccine is generally administered within the first year of age. Under normal circumstances, children should be taken to hospitals or public health prevention stations for vaccination according to the course of treatment. The first dose starts at the third month after birth, followed by the second dose at four months and the third dose at five months old. A booster can be administered when the baby is two years old. The DTP vaccine used in clinics mainly consists of three components: pertussis, diphtheria, and tetanus.

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Written by Li Jian Wu
Pulmonology
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How long is the incubation period for whooping cough?

Once the body is infected with the bacterium that causes whooping cough, the incubation period of this disease is about one to two weeks. The contagion is strongest within two to three weeks after becoming ill. This disease is a respiratory infectious disease, mainly transmitted through airborne droplets, with children under five being the most susceptible to infection. Clinically, vaccination is primarily used to prevent the occurrence of the disease. Once infected, symptomatic treatment is needed, and one can also choose macrolide antibiotics, such as clarithromycin and erythromycin, for treatment.

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Written by Zeng Hai Jiang
Pediatrics
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Is whooping cough without the crowing sound getting better?

Pertussis without a crowing sound indicates recovery. Pertussis, also known as whooping cough, is an acute respiratory infection caused by Bordetella pertussis, commonly seen in children. The progression of pertussis can be divided into three stages: The first stage is the catarrhal stage, also known as the pre-paroxysmal stage. At the early stage, the child shows symptoms similar to the common cold, followed by worsening cough. If the condition is not effectively controlled during this stage, It then progresses to the second stage, the paroxysmal stage. During the paroxysmal stage, the child exhibits characteristic episodic spasmodic coughing and crowing inhalation sounds. This period can last up to two months. Finally, it moves into the recovery stage. In the recovery stage, the frequency and severity of the episodic spasmodic cough and crowing inhalation sounds gradually alleviate. Thus, the absence of a crowing sound in whooping cough is an indication of approaching recovery.

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Written by Li Jian Wu
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How to diagnose the incubation period of pertussis

The incubation period of whooping cough generally has no autonomous discomfort symptoms. If there is close contact with a patient and the body lacks antibodies, suspecting the presence of this pathogen, corresponding auxiliary examinations can be conducted for diagnosis. Bacteriological examinations and fluorescent antibody methods can be performed, using nasopharyngeal swab secretions smear or nasal mucosa impression smear fluorescent antibody staining to detect specific antigens, with an early positive rate of 75%-85%. Complement fixation tests in serology can also be conducted to detect specific antibodies, effectively aiding in the diagnosis of atypical cases.