Common warts, commonly known as verruca vulgaris, are infectious due to human papillomavirus infection and have a high recurrence rate. For example, warts occurring on the feet are called plantar warts, which often have a long disease course and require multiple cryotherapy treatments, even more than ten times, and can recur and reoccur. It is necessary to enhance skin cleanliness, avoid external factors such as injuries, and provide active and effective antiviral treatment and immunomodulatory supportive symptomatic treatment. Early intervention with physical treatments, such as cryotherapy with liquid nitrogen, laser treatment, or even surgical removal of the wart, can be combined with oral medications like thymosin enteric capsules and topical interferon gel to suppress virus replication.