The appendix is connected to the cecum at one end, has a narrow lumen, and is rich in lymphatic tissue. The anatomical basis of the appendix makes it prone to inflammation. Generally, appendicitis is caused by different obstructions in the appendix, such as fecaliths, fecal masses, food residues, and parasites like roundworms, which can all lead to obstruction of the appendix and trigger acute appendicitis. Additionally, gastrointestinal dysfunction can also cause spasms and contractions of the muscles in the appendix wall, affecting the emptying of the appendix and its blood circulation, leading to inflammation of the appendix. Appendicitis requires timely treatment, and surgery might be necessary for symptomatic support.