Is atrophic gastritis of the gastric antrum serious?

Written by Si Li Li
Gastroenterology
Updated on February 03, 2025
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Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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Written by Xie Zheng Yuan
Gastroenterology
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How long does it take to treat atrophic gastritis with erosion?

Atrophic gastritis with erosion is a type of chronic gastritis and has a lengthy course of disease. Through treatment, the erosions may heal within six to eight weeks. However, reversing the atrophy of the gastric mucosa is a long-term and slow process, and there are no specific effective drugs clinically available. Some traditional Chinese medicines and proprietary Chinese medicines may be effective, but it typically takes at least six months. Therefore, the duration required to treat atrophic gastritis with erosion varies from person to person, depending on individual differences.

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Written by Huang Gang
Gastroenterology
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Is atrophic gastritis grade I serious?

Grade I atrophic gastritis is not serious. Atrophic gastritis refers to the atrophy and reduction of the gastric mucosa and glands, and it manifests with symptoms like stomach discomfort, bloating, stomach pain, and loss of appetite. For those with atrophic gastric cancer, it is important to control the diet, avoid overeating, and abstain from spicy, raw, greasy, and irritating foods. This type of chronic digestive system disease, if not properly managed, can frequently relapse and has the potential to become malignant. If the condition can be controlled and does not frequently recur, it generally does not have a significant impact on the body.

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Written by Jiang Guo Ming
Gastroenterology
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Atrophic gastritis with intestinal metaplasia what medicine to take

Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)

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Written by Si Li Li
Gastroenterology
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Symptoms and Treatment of Atrophic Gastritis

Common symptoms of chronic atrophic gastritis include upper abdominal distension, belching, acid reflux, nausea, vomiting, postprandial fullness, heartburn, and indigestion. Gastroscopy can reveal atrophy of the gastric glands in the mucosa, and a definitive diagnosis of chronic atrophic gastritis can be made through biopsy and histopathological examination. In terms of treatment, the first step involves eradicating Helicobacter pylori, using a regimen that includes a proton pump inhibitor, two antibiotics, and a bismuth agent, over a 14-day treatment period. Additionally, treatments aimed at acid suppression, gastric motility enhancement, and gastric mucosal protection are also necessary. Traditional Chinese medicine can also be effective in treating atrophic gastritis. A combined approach utilizing both Western and Chinese medicine can yield better outcomes for the treatment of atrophic gastritis.

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Written by Zhu Dan Hua
Gastroenterology
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Why is a biopsy necessary for atrophic gastritis?

Atrophic gastritis is generally treated with biopsy, which is the standard for diagnosing atrophic gastritis, so biopsy is typically conducted when considering atrophic gastritis. Atrophic gastritis is increasingly common in clinical settings, especially among middle-aged and elderly patients. It begins with symptoms of chronic gastritis, such as abdominal pain, bloating, nausea, and belching, and sometimes may include changes in appetite. Patients usually undergo gastroscopy, which shows atrophy of the gastric mucosa, alterations in red and white patches, or white-like mucosa. Histopathological examination can further support the atrophic changes. In clinical settings, when considering atrophic gastritis, treatment focuses on protecting the stomach and screening for Helicobacter pylori. If Helicobacter pylori is positive, treatment targeting Helicobacter pylori is recommended. Regular gastroscopic examinations are necessary, typically every six months to a year.