How to prevent and treat atrophic gastritis

Written by Jiang Guo Ming
Gastroenterology
Updated on September 09, 2024
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Chronic gastritis includes two types: chronic non-atrophic gastritis and chronic atrophic gastritis. Chronic atrophic gastritis is generally more severe than chronic non-atrophic gastritis and usually accompanies intestinal metaplasia, which some refer to as a precancerous lesion. If chronic atrophic gastritis is present, formal medical treatment is necessary. Initially, it is advisable to check for Helicobacter pylori infection. If an Helicobacter pylori infection is found, timely eradication therapy is recommended, typically using quadruple therapy, which consists of a proton pump inhibitor, two types of antibiotics, and a bismuth agent. If there is no Helicobacter pylori infection, treatment generally focuses on symptomatic relief, such as protecting the gastric mucosa and enhancing gastric motility. Additionally, traditional Chinese medicine has shown satisfactory effects in treating chronic atrophic gastritis. It is also important to maintain good dietary and living habits, prefer light and easily digestible foods, and avoid raw, greasy, spicy, and irritating foods to help maintain a positive state of mind. Regular gastroscopy check-ups are necessary. (Medication should be taken under the guidance of a doctor.)

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Can atrophic gastritis with HP positive lead to cancer?

Chronic atrophic gastritis has a certain risk of cancerous transformation. For patients with chronic atrophic gastritis, the first step in treatment is to administer anti-Helicobacter pylori therapy, which includes a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with a treatment duration of 14 days. Additionally, treatments to suppress stomach acid, protect the stomach lining, promote gastric motility, and repair the stomach mucosa are necessary. Treatment methods also involve traditional Chinese medicine (TCM) diagnoses and oral administration of Chinese herbal medicine. External TCM treatments, such as thunder-fire moxibustion and moxibustion on the Zhongwan acupoint, or the acupoints of spleen-shu and stomach-shu on the back, which strengthen the spleen and benefit qi to nourish the stomach, can also play a significant role in treating this disease.

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Written by Si Li Li
Gastroenterology
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Is atrophic gastritis of the gastric antrum serious?

Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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Written by Wu Hai Wu
Gastroenterology
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What is the cause of recurrent atrophic gastritis?

Recurrent atrophic gastritis is likely caused by Helicobacter pylori infection. When atrophic gastritis recurs, a Carbon-13 urea breath test or Carbon-14 urea breath test should be conducted to detect whether there is an infection of Helicobacter pylori. If the test is positive, a two-week quadruple therapy containing a bismuth agent should be used to eradicate Helicobacter pylori. Consider using a proton pump inhibitor, such as omeprazole or lansoprazole, combined with two of the antibiotics amoxicillin, clarithromycin, metronidazole, and furazolidone, as well as bismuth citrate, to form the quadruple therapy. (Please use medication under the guidance of a doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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Difference between atrophic gastritis and non-atrophic gastritis

Chronic gastritis includes two types: chronic non-atrophic gastritis and chronic atrophic gastritis. The symptoms of both can be similar, such as upper abdominal pain, bloating, nausea, vomiting, acid reflux, and heartburn. Chronic atrophic gastritis tends to be more severe than non-atrophic gastritis. Over the long term, atrophic gastritis may lead to symptoms like fatigue, weight loss, loss of appetite, and even anemia. The main differentiation still requires gastroscopy and pathological examination. Under gastroscopy, chronic superficial gastritis mainly shows mucosal congestion and edema. In atrophic gastritis, due to gland atrophy, the submucosal blood vessels may appear as a net-like or petal-like pattern, and sometimes the mucosa may become granular. Pathological examinations can further clarify the diagnosis.

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What to do about the pain from atrophic gastritis?

Atrophic gastritis is a condition where the mucous membrane of the stomach atrophies, associated with poor neural nutrition and excessive gastric acid secretion, leading to a reduction in the barrier function of the gastric mucosa. To first alleviate pain, proton pump inhibitors can be used to reduce the secretion of gastric acid, and at the same time, gastric mucosal protectants should be used. If there is an infection with Helicobacter pylori, active use of triple or quadruple therapy should be employed to eradicate Helicobacter pylori. It is important to adjust one's diet, eat regularly, and avoid overeating. Greasy and spicy foods should be consumed less, and more bland, soft, and easily digestible foods should be eaten. (Please use medication under the guidance of a doctor.)