Can hepatitis B lead to liver cancer?

Written by Si Li Li
Gastroenterology
Updated on December 28, 2024
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Hepatitis B can cause chronic infection in the body, which may damage liver cells and potentially lead to liver cirrhosis or liver cancer. Therefore, in cases of hepatitis B virus infection, it is necessary to regularly check liver function and hepatitis B virus DNA. If abnormal transaminase levels are found, timely liver-protective and enzyme-lowering treatments should be administered. If the hepatitis B virus DNA reaches a certain level, antiviral treatment should be initiated to potentially slow the progression of hepatitis B developing into liver cirrhosis or even liver cancer. Additionally, carriers of the hepatitis B virus or patients with hepatitis B should take care to rest adequately, avoid excessive fatigue and staying up late, abstain from alcohol, and maintain a light, digestible diet.

Other Voices

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Written by Sun Wei
Surgical Oncology
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Early symptoms of primary liver cancer

Primary liver cancer often shows no obvious symptoms in its early stages. It may present symptoms similar to indigestion, hepatitis, etc. For example, there might be slight discomfort or pain in the upper right abdomen, aversion to oil, or loss of appetite. Generally, regular health check-ups are needed, including imaging studies of the liver such as ultrasound, CT, or MRI. Liver function tests and tumor markers such as alpha-fetoprotein (AFP) should also be performed. In most cases of primary liver cancer, AFP levels will be elevated. Combined with imaging studies, a preliminary diagnosis can be made. A definitive diagnosis requires liver biopsy or confirmation through pathology after surgery.

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Written by Sun Wei
Surgical Oncology
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Can primary liver cancer be treated?

Primary liver cancer is also treatable. Generally, if the primary liver cancer is small and has not widely metastasized, surgical resection can be considered, mainly involving hepatectomy and lymph node dissection. Postoperative comprehensive treatment including chemotherapy and radiotherapy is also applied. For primary liver cancer, interventional chemotherapy, as well as methods like cryotherapy, microwave, and ablation can be considered to control the progression of the disease. Additionally, oral targeted therapy such as sorafenib can be used. If primary liver cancer is widely metastasized at the time of detection, there generally aren’t very effective treatment options, and the average survival period might be around six months, with poor treatment outcomes.

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Written by Sun Wei
Surgical Oncology
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The difference between primary liver cancer and secondary liver cancer.

Primary liver cancer generally refers to tumors whose cancer cells originate from the liver itself or from the intrahepatic bile ducts. Secondary liver cancer usually refers to cancer that has metastasized to the liver from other parts of the body, which is the main difference between the two. Additionally, primary liver cancer might progress rapidly, potentially resulting in a short survival time, especially in cases of large, inoperable tumors, where most survival times range from half a year to about a year. In contrast, secondary liver cancer might have a longer survival time, and initial symptoms are generally milder. Also, tumor markers like alpha-fetoprotein (AFP) tend to be higher in primary liver cancer, whereas in secondary liver cancer, this marker may be normal.

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Written by Du Ning
Hepatobiliary Surgery
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Can gallbladder stones turn into liver cancer?

Long-term pathological changes from hepatobiliary calculi can lead to liver cancer. Hepatobiliary calculi generally refer to intrahepatic bile duct stones. When these stones grow in a single duct and gradually increase in number and size, they can cause obstruction of the bile duct. Obstruction of the bile duct subsequently leads to cholangitis, which involves repeated inflammatory irritation. This, in turn, can cause malignant transformation of the bile duct cells. Following this transformation, a tumor forms, which can develop into cholangiocellular carcinoma, a type of liver cancer. Therefore, if intrahepatic bile duct stones cause long-term inflammatory stimulation, it can lead to cancerous changes and result in liver cancer. Thus, if intrahepatic bile duct stones have already caused noticeable clinical symptoms such as abdominal pain, fever, and liver function abnormalities, aggressive surgical treatment should be considered.

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Written by Sun Wei
Surgical Oncology
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Can primary liver cancer patients eat eggs?

Patients with primary liver cancer can also eat eggs, as there are no specific prohibitions against it. Eggs are a high-protein food. While many people worry that eating eggs might increase the burden on the liver, there is actually no need for concern. If a patient has a good appetite and can eat well, consuming some eggs to increase protein intake can help enhance body resistance and support antitumor treatment. In addition to eggs, liver cancer patients should also consume other high-quality proteins such as fish and protein powder. These are all beneficial. Of course, the choice should also be based on the patient's own preferences. Additionally, it is advisable to drink plenty of water and eat fresh vegetables and fruits.