How long to take aspirin for Kawasaki disease

Written by Li Jiao Yan
Neonatology
Updated on September 23, 2024
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The current pathogenesis of Kawasaki disease is not yet clear, but one of its main pathological changes is a systemic vasculitis. During an outbreak of Kawasaki disease, the blood viscosity increases primarily due to platelet aggregation. Typically, oral aspirin is administered to prevent this inflammation and to treat platelet aggregation. The dosage is generally reduced gradually once the fever subsides, with maintenance doses lasting about six to eight weeks. If coronary artery lesions are present, the duration of medication is extended until the coronary arteries return to normal before discontinuing the drug.

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Written by Li Jiao Yan
Neonatology
1min 23sec home-news-image

Is the spirit of Kawasaki disease good?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear cause and is generally prevalent in infants and young children, with 80% of cases occurring in children under five years old. The mechanism of the disease is also not very clear. Its main pathological presentation is systemic vasculitis, often involving the coronary arteries. The primary clinical symptoms include high fever, which is unresponsive to antibiotic treatment, conjunctival congestion, diffuse oral congestion, strawberry tongue, indurative edema of the hands and feet, and palmoplantar erythema. Additionally, it may affect the heart, leading to conditions such as pericarditis, myocarditis, endocarditis, and arrhythmias. During the acute phase of Kawasaki disease, the high fever and diffuse oral mucosal congestion can affect the child's mental state. If the heart is involved, there may be abnormalities in heart rate and heart function, which can also lead to a poor mental state. Therefore, if Kawasaki disease is confirmed, it definitely requires active treatment.

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Written by Li Jiao Yan
Neonatology
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Does Kawasaki disease cause a rash on the face?

The pathogenesis of Kawasaki disease is unclear, and the main pathological change is systemic vasculitis. Typically, the rash is a polymorphic erythema or a scarlatiniform rash, primarily occurring on the trunk. Generally, facial rashes are rare, but it's not entirely impossible for rashes to appear on the face. Therefore, if a baby develops a rash on the face without other infections, Kawasaki disease might also present this symptom.

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Written by Li Jiao Yan
Neonatology
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What should not be eaten with Kawasaki disease?

One of the main pathological changes in Kawasaki disease is systemic vasculitis. Clinically, common symptoms include fever, high fever, recurrent fever, conjunctival congestion, significant oral mucosal congestion, strawberry tongue, enlargement of neck lymph nodes, and peeling of the hands and feet. In cases of Kawasaki disease, oral mucosal congestion is a common complication, hence during the period of Kawasaki disease, it is advised not to consume irritating, spicy, or hot foods. These might exacerbate the child's discomfort, affect their nutrient absorption, and potentially worsen the condition. Therefore, during the illness, it is preferable to focus on bland, easy-to-digest foods.

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Written by Li Jiao Yan
Neonatology
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How many days can Kawasaki disease be cured?

Kawasaki disease is a syndrome of mucocutaneous lymph node syndrome, the cause of which is unclear, as is the pathogenesis of the disease. The pathological changes are mainly systemic vasculitis, which is prone to secondary damage to the coronary arteries. It has a relatively long course. If fever occurs, the fever can persist for 1-2 weeks. Generally, special medications such as aspirin are required for treatment. Usually, treatment is for 3 days, and after the fever subsides, the dosage is gradually reduced, maintained for 6-8 weeks. If there is secondary coronary artery damage, the duration might be longer. In cases of severe coronary damage, the duration of the disease may be several months or even years, depending on the specific condition of the disease. Kawasaki disease is a self-limiting disease. Usually, if there is no significant coronary artery damage, after symptom control, comprehensive examinations are conducted 1 month, 3 months, 6 months, and 1-2 years after discharge, mainly heart examinations such as electrocardiograms and echocardiograms. If there is a combination of coronary artery aneurysms, long-term follow-up is required, with an examination every six months to one year until the coronary aneurysm disappears or if there is combined damage to the coronary artery structure, long-term follow-up is needed.

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Written by Li Jiao Yan
Neonatology
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Kawasaki disease peeling symptoms

Kawasaki disease is a disease with unclear etiology and unclear pathogenesis of the autoimmune system. Its main pathological change is systemic vasculitis, commonly occurring in the coronary arteries. At the onset, symptoms in the hands and feet include stiff swelling and erythema during the acute phase. In the recovery phase, membranous peeling occurs at the junction of the skin and the nail base of fingers and toes, and there are transverse grooves in the nails. In severe cases, the nails of the fingers and toes may also fall off. Additionally, its skin manifestations include polymorphic skin plaques and scarlet fever-like rashes, which commonly appear in the first week of the disease, with redness and peeling of the skin around the anus.