Gestational diabetes standards

Written by Zhao Dan
Orthopedics
Updated on September 16, 2024
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Before addressing this question, let's first clarify another concept: if diabetes is diagnosed before pregnancy, this is referred to as pre-existing diabetes in pregnancy, which is different from gestational diabetes. Gestational diabetes refers to cases where there is no pre-existing diabetes diagnosis before pregnancy, but abnormal blood glucose levels are detected after becoming pregnant. Generally, a glucose screening test is conducted between the 24th and 28th weeks of pregnancy. Currently in China, there are two approaches: the one-step and the two-step methods. The one-step method involves a direct 75-gram oral glucose tolerance test. However, most of China uses the two-step method, which starts with a 50-gram glucose challenge test. If the blood glucose level one hour after eating is greater than or equal to 7.8 mmol/L, a 75-gram oral glucose tolerance test is recommended. For the 75-gram glucose test, the fasting blood glucose level should generally be less than or equal to 5.6 mmol/L, one hour post-glucose intake should be 10.3 mmol/L, two hours post-glucose should be 8.6 mmol/L, and three hours post-glucose should be 6.7 mmol/L. If two or more of these values exceed the diagnostic criteria, gestational diabetes can be diagnosed. If only one value is abnormal, impaired glucose tolerance can be diagnosed. It is recommended that anyone who experiences abnormal blood glucose levels during pregnancy undergo another 75-gram oral glucose tolerance test six months post-pregnancy to determine if blood glucose levels are still abnormal and whether treatment should continue.

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Causes of Gestational Diabetes

Gestational diabetes refers to the abnormality of blood sugar levels that occurs during pregnancy, at which time it is called gestational diabetes. The reason for the occurrence of gestational diabetes is due to significant changes in the body's endocrine hormones after pregnancy. The body releases many hormones, such as estrogen and progesterone, which can increase insulin resistance. Thus, a much greater amount of insulin is needed to maintain normal blood sugar levels. If the pancreatic beta cells are not sufficient to compensate for the increased insulin secretion needed to meet the normal metabolic requirements caused by these resistance factors, then elevated blood sugar and abnormal glucose metabolism occur, ultimately leading to gestational diabetes.

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Gestational diabetes symptoms

During pregnancy, there are two scenarios concerning diabetes: one is where diabetes is diagnosed before pregnancy, referred to as pregestational diabetes combined with pregnancy. The other scenario is where the sugar metabolism is normal before pregnancy, or there is an underlying reduced glucose tolerance, and diabetes appears or is diagnosed during pregnancy, also known as gestational diabetes. Over 80% of diabetic pregnant women have gestational diabetes. Typically, gestational diabetes doesn't show clear symptoms of the classic "three polys and one less" - excessive drinking, eating, urination, and weight loss. Some women with gestational diabetes may experience itching of the vulva, caused by repeated infections with Candida albicans. Additionally, gestational diabetes may lead to conditions like fetal macrosomia and polyhydramnios during pregnancy, and pregnant women with gestational diabetes are more prone to infections.

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Gestational diabetes symptoms

Gestational diabetes refers to the abnormal glucose tolerance that occurs during pregnancy, typically characterized by mild, asymptomatic elevated blood sugar levels without obvious symptoms such as dry mouth, excessive thirst, and frequent urination. However, when blood sugar levels are high, symptoms typical of diabetes such as dry mouth, excessive thirst, and frequent urination may occur. If excessive amniotic fluid, a large fetus, or recurrent infections of the external genitalia occur during pregnancy, it is important to be vigilant for the presence of diabetes. It is generally recommended that patients undergo the OGTT (Oral Glucose Tolerance Test) during the mid-stage of pregnancy to confirm whether gestational diabetes is present. Women's blood sugar levels generally return to normal after childbirth, but the risk of developing diabetes later increases significantly. Therefore, patients with gestational diabetes should be screened for diabetes 6-12 weeks postpartum and monitored over the long term.

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How to treat diabetic foot?

Diabetic foot is one of the most severe complications of diabetes. It is caused by a combination of factors including peripheral vascular disease and diabetic peripheral neuropathy associated with diabetes. In such cases, treatment can involve internal medicine, interventional vascular treatment, and surgical treatment cooperatively managed by multiple vascular departments. Early treatment focuses on controlling blood sugar, improving circulation, and nourishing nerves. If ulcerations and skin breakdown have already occurred in the foot, further debridement and anti-infection treatments are necessary. It is essential to conduct an ultrasound of the lower limb vessels to assess for any vascular narrowing. If severe vascular occlusion occurs, vascular surgery may be needed to restore blood flow. In cases of severe diabetic foot with infection, surgical debridement or even amputation may be necessary. Thus, it is crucial to control blood sugar well in the early stages of diabetes to prevent these complications and potentially avoid the onset of diabetic foot.

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incidence of gestational diabetes

Gestational diabetes refers to diabetes that appears or is diagnosed during pregnancy, or any degree of glucose tolerance abnormality, which is classified as an independent type of diabetes. Diabetes combined with pregnancy or gestational diabetes can pose serious risks to the health of both mother and child. Before national screening of blood sugar levels during pregnancy was initiated, the detection rate of gestational diabetes was not very high, only 0.24%. However, with the widespread implementation of blood sugar screening during pregnancy, the current incidence rate of gestational diabetes is approximately 1% to 5%.