If rickets is not treated, what will be the impact?

Written by Mo Ming Hua
Pediatrics
Updated on November 09, 2024
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Rickets, if untreated, mainly involves changes in skeletal deformities and motor function in children. Rickets is primarily caused by a deficiency in vitamin D, which is essential for promoting the absorption of calcium. A deficiency in vitamin D leads to reduced calcium absorption. Lower calcium absorption results in a calcium deficiency in the body, which in turn causes changes in the bones. In the early stages of vitamin D deficiency, the main symptoms are increased neural excitability, which may manifest as startle reactions, irritability, restlessness, and excessive sweating. During the active phase, symptoms of increased nervous system excitability become more pronounced, mainly presenting as skeletal deformities. What aspects do these skeletal deformities affect? One is the softening of the skull, pigeon chest, funnel chest, and changes resembling wristbands and anklets. If the condition worsens further, it can present as X-shaped legs, O-shaped legs, and spinal deformities. Thus, if rickets progresses, it can lead to skeletal deformities and impairments in motor functions, among other issues.

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Written by Tong Peng
Pediatrics
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Can rickets be treated with vitamin D3?

Rickets can be treated with Vitamin D3; first, we need to understand the pathology of the disease. It is a metabolic, obstructive disease caused by a deficiency of Vitamin D. Often, this deficiency leads to impaired calcium absorption in the body, causing osteoporosis and bone deformity. Infants typically exhibit symptoms like square skulls, pigeon chests, outward flaring ribs, bow legs, and knock knees. Additionally, it affects the baby's sleep quality. The lack of Vitamin D can increase the baby's neural excitability, leading to poor sleep and easy waking. Moreover, severe cases can affect growth and development. Presence of these symptoms should be confirmed by laboratory testing of 25-hydroxy Vitamin D3 to determine specific levels and choose the appropriate dose of Vitamin D3 supplementation. It is also encouraged to promote children's physical activity and exposure to sunlight to enhance the body's synthesis of Vitamin D, which is beneficial for bone development. (Medication should be administered under the guidance of a professional doctor.)

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Written by Zhang Xian Hua
Pediatrics
1min 8sec home-news-image

Is pillow baldness rickets?

Balding at the back of the head is a common clinical manifestation of rickets, but it does not mean that balding at the back of the head is equivalent to rickets, as there are many causes for this condition. In children with rickets, due to a lack of vitamin D leading to calcium deficiency, their neural excitability increases, which can affect the baby's sleep and cause restless sleep leading to balding at the back of the head. However, children who are in poor nutritional condition might also experience deficiencies in trace elements, such as a lack of zinc or iron, which can also lead to sleep disturbances and balding at the back of the head, indicating that the cause may not necessarily be rickets. Additionally, a small number of children might have an inherent condition of increased neural excitability that affects sleep, leading to balding at the back of the head, which also isn't due to rickets. Therefore, if balding at the back of the head occurs, it is advisable to visit a hospital’s pediatric healthcare department or pediatric outpatient clinic for a consultation and check-up, to actively treat and manage based on the underlying cause.

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Written by Li Jiao Yan
Neonatology
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Rickets is a deficiency of what?

Rickets is caused by a deficiency of what? For rickets, its main gold standard for diagnosis is based on the results of blood biochemistry and skeletal X-ray examinations. Generally, the deficiency in rickets is mainly due to insufficient levels of vitamin D, which then leads to disturbances in calcium and phosphorus metabolism. Typically, this is characterized by low levels of 25-hydroxyvitamin D3 in the body, along with decreased levels of blood calcium and phosphorus, manifesting as deficiencies in calcium, phosphorus, and vitamin D. However, in children, rickets could also be caused by other factors, such as abnormalities in liver or kidney function, or congenital hereditary diseases. Generally, further tests are needed to confirm rickets. If other special causes are ruled out, timely supplementation of vitamin D and appropriate exposure to sunlight, along with calcium supplementation, can effectively cure the disease.

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Written by Li Jiao Yan
Neonatology
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Can rickets be treated by injection?

Rickets is primarily caused by a deficiency of vitamin D, leading to a disturbance in calcium and phosphorus metabolism in the body, which results in abnormal bone development. It is a systemic nutritional and chronic disease. The main treatment is to supplement a sufficient dosage of vitamin D, generally administered orally. The choice of vitamin D formulation, dosage, duration of treatment, whether it is administered once or multiple times, and whether supplementation is oral or intramuscular, should be determined based on the specific situation of the child. Relevant tests are generally required, and the doctor will develop a treatment plan based on the child's condition. The route of administration should also be decided based on the condition of the disease.

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Written by Zeng Hai Jiang
Pediatrics
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The difference between rickets and dwarfism.

Rickets is caused by a deficiency of vitamin D in infants and young children, leading to disturbances in calcium and phosphorus metabolism and resulting in skeletal abnormalities as a characteristic of this chronic nutritional disease. Typical symptoms can include changes in the bones, especially in the fastest growing parts of the skeleton, and can affect muscle development and changes in neural excitability. Symptoms such as a "ping pong ball" head, square skull, pigeon chest, funnel chest, and eversion of the rib margins are also observed. Diagnosis is made through examinations such as vitamin D levels and skeletal X-rays. Dwarfism, on the other hand, is a growth disorder caused by a deficiency of growth hormone from the anterior pituitary gland before puberty. Its clinical manifestations are primarily growth disturbances, characterized by a short, proportionate stature. Adults with this condition often retain a child-like appearance, and their bone development is delayed with bone age younger than their chronological age. Intellect corresponds to their age, and sexual development may also be disrupted.