Mycoplasma infection is clinically treated by using antibacterial drugs orally or intravenously to eradicate the mycoplasma. The most commonly used drugs are macrolide antibiotics, such as erythromycin, roxithromycin, azithromycin, or clarithromycin. Usually, choosing one of these is sufficient. Additionally, treatment should be based on the location of the infection and the specific symptoms of the patient. If the infection affects the respiratory system and causes symptoms like coughing and expectoration, medications to thin the mucus should be selected. Also, treatments to reduce fever and alleviate symptoms should be administered.