Causes of Alzheimer's Disease

Written by Zhou Yan

Geriatrics

Updated on April 10, 2025

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The causes of Alzheimer's disease are related to multiple factors. For instance, advanced age is the most significant risk factor for Alzheimer's disease, with the incidence increasing by 5% with each additional year. Secondly, it is related to gender, with women being more prone to Alzheimer's disease. Additionally, there is a certain relationship with genetics. The fourth factor is vascular factors, such as hypercholesterolemia, hyperhomocysteinemia, diabetes, and hypertension. The fifth factor is lifestyle, including smoking, excessive drinking, diet, sleep disorders, depression, and obesity, all of which are risk factors for Alzheimer's disease.

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Written by Zhang Hui

Neurology

1min 10sec

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Late-stage symptoms of dementia

In the later stages of dementia, symptoms become very severe. Patients experience significant impairment in memory function, forgetting not only recent events but also events from the past. Additionally, patients show obvious impairments in visuospatial abilities, having trouble locating the bathroom in their own home, and often getting lost when they go out. There is also a noticeable change in behavior, with patients exhibiting aggression, cursing, and inappropriate actions like urinating or defecating in random places. Some patients may experience recurrent visual and auditory hallucinations. As the disease progresses, elderly patients may eventually become bedridden for life, not interacting with anyone, remaining silent, and refusing to eat. They ultimately may die from complications such as lung infections, urinary tract infections, malnutrition, and bedsores. Therefore, the symptoms of dementia in its later stages are quite severe, with cognitive impairments, abnormal mental and behavioral symptoms, and various infections all posing serious threats to the health of the elderly.

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Written by Zhang Hui

Neurology

46sec

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Early signs of dementia

Dementia in the elderly, mainly refers to Alzheimer's disease. Early signs of this condition may manifest as some forgetfulness. For example, a patient might forget to add salt while cooking, or forget to bring their keys when leaving the house. These clinical signs should be highly alarming and should not be dismissed as mere forgetfulness, ignoring further examinations and treatments. It is recommended that if the elderly show signs of diminished memory function, they should promptly visit a hospital. Comprehensive assessments and further tests, including brain MRI scans, should be conducted to check for significant atrophy in brain areas such as the temporal lobes and hippocampus. If dementia is diagnosed, prompt intervention and treatment should be pursued.

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Written by Zhang Hui

Neurology

1min 4sec

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incidence of senile dementia

Dementia in the elderly has a very noticeable high incidence trend worldwide and in China, with many people over the age of 65 suffering from this disease. Statistics show that in Western countries, the incidence of dementia in the elderly might be around 3%-8%. In China, the incidence among the elderly over 65 may also be around 5%. Therefore, the number of elderly people suffering from this disease is very large, and thus it is essential to pay attention to this disease. This disease is mainly caused by the death of nerve cells due to many reasons. Currently, there is no effective cure for this disease, but there are some drugs that can alleviate the symptoms. These drugs mainly include cholinesterase inhibitors, which can increase the content of acetylcholine in the brain, improving the level of cognitive function in patients. Additionally, symptomatic treatment should be noted to prevent lung infections, malnutrition, and other complications in the elderly.

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Written by Zhang Hui

Neurology

47sec

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What is the full name of dementia?

Senile dementia mainly refers to Alzheimer's disease, a condition with a relatively high incidence rate among the elderly population, and it is the most common neurodegenerative disease. The specific causes and mechanisms of this disease are not particularly clear. Under the influence of various factors, degeneration and death of the temporal lobe, hippocampus, and neurons occur, leading to a series of clinical manifestations. Initially, it mainly manifests as a decline in recent memory function, often forgetting recent events. As the disease progresses, there is a decline in calculating ability and judgment, significant spatial dysfunction, personality changes, and psychiatric symptoms.

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Written by Zhang Hui

Neurology

1min 2sec

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symptoms of dementia in the elderly

The symptoms of dementia mainly include: First, impaired memory function, where the patient’s memory loss is very noticeable. Initially, they may not remember recent events, and as the disease progresses, they may not remember past events, such as forgetting how many children they have or their children’s names. Second, it mainly involves symptoms of impairment in other cognitive areas, such as visual spatial dysfunction, manifesting as not being able to find the bathroom at home, getting lost after going out, and not being able to find the way back home. Additionally, the patient's ability to understand, calculate, and judge will also be significantly impaired, and they cannot master previously learned knowledge and skills. Third, in the late stages, some psychiatric symptoms appear, including visual and auditory hallucinations, and agitated behaviors such as hitting and cursing. Additionally, the patient may also experience some physical weakness, muscle atrophy, and incontinence.