Late-stage symptoms of senile dementia

Written by Zhang Hui
Neurology
Updated on December 23, 2024
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Elderly dementia generally refers to Alzheimer's disease. This disease begins slowly and progressively worsens, with symptoms becoming increasingly severe. In the later stages of dementia, symptoms are numerous, mainly reflected in the following aspects: First, patients may exhibit significant personality changes. For example, a person who was originally gentle may become irritable and prone to aggressive behaviors such as hitting or yelling at others, and may even experience incontinence. Second, a patient's overall cognitive functions completely collapse, with a comprehensive decline in memory, as well as significant impairments in computational abilities, judgment, and comprehension. There are also problems with time orientation, with patients unable to distinguish between day and night. Additionally, patients may experience severe malnutrition, develop bedsores, and suffer from serious complications such as pulmonary infections and urinary tract infections.

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Written by Zhang Hui
Neurology
1min 13sec home-news-image

Can senile dementia be cured?

Dementia in the elderly is a clinical syndrome caused by the irreversible death of neurons. So far, the mechanism of the disease is not particularly clear, making it very difficult to cure dementia completely. However, there are some corresponding treatment methods that can delay the progression of the disease and improve the quality of life of patients as much as possible. These treatments mainly include exercise therapy, which involves getting patients to participate in appropriate physical activities that can promote cognitive development. In addition, letting patients listen to music more often, interact more with others, and continue learning can also delay the progression of aging. Furthermore, there are some medications that can improve the symptoms of dementia. Currently, the most commonly used worldwide are acetylcholinesterase inhibitors, which can increase the levels of acetylcholine and thereby improve cognitive function to some extent and slow the progression of the disease. Additionally, if elderly individuals exhibit some psychiatric symptoms, they can also be given some atypical antipsychotic medications to alleviate the condition.

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Written by Zhang Hui
Neurology
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Is senile dementia hereditary?

The disease referred to as dementia mainly refers to Alzheimer's disease. Only a very small number of cases are hereditary, where patients have a certain family history caused by genetic mutations, thus having some hereditary traits. However, the vast majority of Alzheimer's cases are sporadic, unrelated to genetic mutations, and these sporadic cases are not hereditary, so there is no need to worry about transmitting it to offspring. Nevertheless, it is important to note that, with the progression of population aging, the incidence of this disease remains relatively high, especially for those over the age of 65, who need to pay close attention to this disease. If a patient exhibits a decline in memory function, do not assume it is just forgetfulness; it is crucial to visit a hospital for diagnosis and timely treatment.

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Written by Zhang Hui
Neurology
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Causes of Dementia

At present, the specific causes and mechanisms of Alzheimer's disease are not very clear, but they are mainly divided into two categories. The first category is hereditary, where some Alzheimer's disease cases have a clear family history and involve some genetic mutations. These genetic mutations lead to the deposition of abnormal proteins within neurons, causing irreversible neuronal death, which is the main reason for familial Alzheimer’s disease. The second category is sporadic Alzheimer’s disease, for which no clear pathogenesis has been identified. Research suggests that factors such as oxidative stress, trauma, cerebrovascular disease, cerebral ischemia, and other factors, including metabolic conditions leading to dementia, are related to the occurrence of sporadic Alzheimer's disease. Therefore, the causes of Alzheimer’s disease include two main categories: the first is caused by genetic mutations, and the second is caused by various adverse factors leading to neuronal death.

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Written by Zhang Hui
Neurology
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Alzheimer's disease is also called dementia.

Alzheimer's disease, also known as dementia in the elderly, was first identified abroad and thus named after the discoverer, Alzheimer. It is one of the most common neurodegenerative diseases in neurology, with a very high incidence among people over 65 in China and worldwide. The disease mainly affects patients' cognitive functions. Initially, patients do not meet the criteria for dementia and primarily exhibit a decline in memory. As the disease progresses, the decline in memory worsens, and patients begin to forget both recent and past events. Additionally, they may experience impairments in visuospatial abilities, judgment, comprehension, and learning capabilities. In the later stages, psychiatric symptoms and personality changes may appear, such as visual hallucinations, shouting, and gesturing wildly, among various other clinical manifestations.

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Written by Zhang Hui
Neurology
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How is Alzheimer's treated?

The treatment of Alzheimer's disease mainly includes the following aspects. First, enhance care to prevent accidents. Patients with Alzheimer's may get lost, forget to turn off fires or gas, etc., so it is essential to strengthen care to prevent accidents. Second, encourage the elderly to read more books and newspapers and enhance learning, which can effectively slow down the progression. Third, have the elderly interact more with others and exercise more. This can strengthen their physical health and, to some extent, delay the development of Alzheimer's disease. Another aspect is drug treatment, which mainly includes acetylcholinesterase inhibitors and some NMDA receptor antagonists. These can improve the symptoms to some extent and enhance the quality of life. Additionally, in the later stages of Alzheimer's, some psychiatric symptoms such as visual hallucinations and aggressive behavior like hitting or yelling may occur. Appropriate atypical antipsychotic drugs can be administered for treatment.