Prickly heat is a common skin disease that often occurs in summer. For the treatment of prickly heat, we divide it into systemic treatment and topical treatment. Systemic treatment mainly involves taking antihistamines orally, such as loratadine tablets, when itching is severe. If there is a pus infection, it is recommended to use antibiotics for treatment. Another method is the topical treatment of prickly heat, which involves the use of cooling powders locally, such as prickly heat powder or cooling and itching-relieving washes, such as calamine lotion or menthol tincture. In cases of pustular prickly heat, calamine or berberine powder can be used topically.