Can amenorrhea undergo IVF?

Written by Hou Jie

Obstetrics and Gynecology

Updated on January 20, 2025

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There are many causes of amenorrhea in women in our country, with the most common causes being hypothalamic disorders, pituitary disorders, and ovarian disorders. Other endocrine diseases, such as congenital adrenal hyperplasia and thyroid dysfunction, can also lead to ovulation disorders and the symptoms of amenorrhea. If amenorrhea occurs and there is a desire for childbirth, it is advisable to seek timely medical treatment at a professional reproductive hospital. This allows for systematic regulation of menstruation and comprehensive treatment based on the specific causes of amenorrhea, aiming to possibly enhance fertility and improve our infertile condition.

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What are the harms of premature menopause?

The normal age of menopause for women in our country is around 49 years old. If menopause occurs during this period, it's generally not a big issue. However, if menopause occurs prematurely, it typically indicates a decline in ovarian function or early ovarian failure. This can cause disruptions in marital relations for women, and if menopause happens too early, it can lead to premature symptoms of menopause. Symptoms such as hot flashes, sweating, irritability can occur, and in severe cases, it may lead to diseases related to blood pressure and cardiovascular health. Therefore, premature menopause does have an impact on health. If these symptoms appear prematurely, it is crucial to go to the hospital for appropriate adjustment and treatment.

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Causes of Amenorrhea

Amenorrhea can be physiological or pathological. Physiological amenorrhea, for example, occurs during the breastfeeding period when menstruation is irregular for three consecutive months; this is considered normal. Also, some patients may experience temporary amenorrhea due to medications used to treat conditions such as endometriosis, which is also normal. Pathological amenorrhea, commonly seen in clinical settings, includes conditions such as ovarian dysfunction, severe intrauterine adhesions, premature ovarian failure, or other endocrine disorders, which can result in the absence of menstruation. It is essential for individuals experiencing amenorrhea to undergo relevant medical examinations to identify the cause, followed by appropriate treatments based on the findings.

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How to regulate amenorrhea with no vaginal discharge?

Amenorrhea without vaginal discharge is a normal physiological phenomenon. Amenorrhea occurs due to ovarian failure, which results in no normal ovulation and a significant decrease in estrogen levels, or very low levels of estrogen. Consequently, the secretions from the cervix and vagina decrease, leading to an absence of vaginal discharge—a normal occurrence that does not require intervention. However, if there is an increase in vaginal discharge after amenorrhea, or if the discharge is abnormally colored and accompanied by itching of the vulva, it could indicate vaginitis, which would require prompt examination and treatment. Therefore, the absence of vaginal discharge following amenorrhea does not require intervention.

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How to regulate amenorrhea for one year?

If a woman under 40 experiences amenorrhea for a year, it is advisable to check the six sex hormones. If there is an increase in luteinizing hormone and follicle-stimulating hormone, it indicates menopause. However, menopause before 40 is called premature ovarian failure, and hormone replacement therapy is needed. This treatment can delay aging in women and improve post-menopausal symptoms. If menopause occurs after the age of 40, it is a natural state. Every woman will go through menopause, and if menopausal symptoms occur, hormone replacement therapy can also be used.

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Can amenorrhea undergo IVF?

Whether amenorrhea is suitable for IVF depends firstly on the cause of the amenorrhea. If the amenorrhea is due to ovarian failure, with an AMH value less than 1, indicating diminished ovarian function, IVF would not be successful in this scenario. However, if the AMH, indicating ovarian reserve, is greater than 1 and the amenorrhea is caused by hormonal imbalances, then IVF can be considered. If the amenorrhea is due to uterine adhesions, adhesion dissection can be performed. If, following the dissection, the endometrium develops well and the adhesions are treated, IVF can be considered. Moreover, if the amenorrhea is associated with conditions like galactorrhea-amenorrhea syndrome or polycystic ovarian syndrome, which are also due to hormonal imbalances, adjusting hormone levels to normal can also make IVF a viable option. Therefore, whether IVF is possible with amenorrhea depends on identifying the cause of the amenorrhea, and decisions can be made based on that.