The causes of cerebellar atrophy are quite diverse: First, some genetic diseases can lead to significant cerebellar atrophy, such as hereditary cerebellar ataxia, where patients experience obvious cerebellar atrophy. Currently, there are no effective treatments for this condition. Second, chronic alcohol poisoning from long-term drinking can lead to alcohol intoxication, which particularly damages cerebellar cells and causes cerebellar atrophy. Third, there are also some vascular diseases, such as cerebellar thrombosis. Recurrent cerebellar thrombosis can cause cerebellar atrophy. Fourth, other conditions like cerebellar inflammation and cerebellar tumors can also cause significant cerebellar atrophy. Fifth, some neurodegenerative diseases can also damage the cerebellum, such as multiple system atrophy with olivopontocerebellar atrophy, which also leads to cerebellar atrophy and manifests as ataxia.