Can tuberculosis be cured completely?

Written by Wang Xiang Yu
Pulmonology
Updated on January 29, 2025
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Whether tuberculosis can be completely cured varies from person to person. Most cases of tuberculosis, especially initial occurrences of pulmonary tuberculosis, can be cured in more than 80 to 90 percent of patients if they undergo standardized anti-tuberculosis treatment. However, it is essential that the treatment is standardized; it is not appropriate to simply take medication for one or two months and then stop when symptoms seem to disappear. The treatment duration for pulmonary tuberculosis is considered to be at least six months, and for some patients, it may even extend to a year. However, not all cases of pulmonary tuberculosis can be completely cured. A small percentage of patients may not achieve complete eradication due to resistance to tuberculosis bacteria or intolerance to the side effects of tuberculosis medications. In such cases, the prognosis might be poor, and some individuals may succumb to tuberculosis due to these factors.

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Written by Yuan Lin Yan
Infectious Disease
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Is tuberculosis contagious?

Not all cases of tuberculosis are infectious. Some tuberculosis cases are infectious in the early stages but become non-infectious after proper treatment. Patients with open tuberculosis are highly contagious because their sputum contains tuberculosis bacilli. These bacilli can be released into the air through coughing, sneezing, laughing, or loud speaking, and can cause infection when inhaled by others. Some tuberculosis patients do not have detectable bacilli in their sputum, and their infectiousness is relatively much lower.

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Written by Wang Xiang Yu
Pulmonology
40sec home-news-image

Does tuberculosis get inherited?

Is tuberculosis hereditary? Tuberculosis is not a hereditary disease; it is an infectious disease. Infectious diseases and hereditary diseases are two completely different concepts. Tuberculosis is generally infectious, which means that in a family, if parents are infected, they can easily transmit the tuberculosis bacteria to their children or others around them. Therefore, many people might mistakenly believe that tuberculosis is hereditary. However, this is not the case; tuberculosis is transmitted through the tuberculosis bacteria.

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Written by Yuan Lin Yan
Infectious Disease
1min 21sec home-news-image

Can tuberculosis be cured?

Tuberculosis can be cured if it is detected early and treated promptly with standard anti-tuberculosis therapy, resulting in a very good prognosis. However, it is very unfortunate if detection is delayed or if standard treatment is not administered, as the tuberculosis may recur or infect with drug-resistant strains, causing permanent damage to lung function. Advanced pulmonary lesions or significant hemoptysis can be life-threatening. Currently, the treatment of tuberculosis involves chemotherapy, with principles including early treatment, combination therapy, appropriate dosing, regularity, and completeness, usually lasting at least six months. Common first-line anti-tuberculosis medications include isoniazid, rifampin, ethambutol, and pyrazinamide. Initially, a two-month intensive phase of treatment with isoniazid, rifampin, ethambutol, and pyrazinamide is followed by a four-month continuation phase with isoniazid and rifampin. During the treatment of tuberculosis, it is important to enhance one's resistance and immune function and to improve nutrition to facilitate recovery. (Use medications under the guidance of a doctor.)

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Written by Li Jiao Yan
Neonatology
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Does the BCG vaccine prevent tuberculosis?

The BCG vaccine primarily prevents infection by the tuberculosis bacillus, so it can prevent pulmonary tuberculosis. The protective effect of the BCG vaccine is mainly achieved through inducing a cell-mediated immune response. After vaccination, a primary infection is formed, which is processed by macrophages that transmit the antigen information to immune-active cells, leading to the differentiation and proliferation of T cells and the formation of sensitized lymphocytes. When the body is re-infected with the tuberculosis bacillus, the macrophages and sensitized lymphocytes are activated, causing a specific immune response in the body, thereby resisting the infection by the tuberculosis bacillus. Therefore, the BCG vaccine mainly prevents pulmonary tuberculosis.

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Written by Wang Xiang Yu
Pulmonology
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Is tuberculosis easily contagious?

Whether tuberculosis (TB) is easily transmitted primarily depends on the source of infection, which refers to the TB patients and the amount of Mycobacterium tuberculosis in their sputum. If TB bacilli can be detected in their sputum, and the quantity is substantial, then their infectiousness is indeed higher. However, if the TB patient has undergone treatment, or if there are only a few TB bacilli in their sputum, or none at all, then their infectiousness may not be as significant. The second factor is the mode of transmission, which mainly occurs through the respiratory tract. If TB patients can be isolated timely, or if they wear masks, and their sputum is properly managed, for example by wrapping the sputum in paper and burning it, then they are less likely to transmit the disease to others. TB generally involves susceptibility issues; even if someone has been vaccinated with BCG or the TB vaccine, they can still be reinfected. Therefore, controlling these three transmission pathways is essential to minimize the risk of contracting TB.