What is tuberculosis?

Written by Wang Xiang Yu
Pulmonology
Updated on September 24, 2024
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Tuberculosis is a disease where the bacterium Mycobacterium tuberculosis infects the lungs. It is a persistent bacterium that grows slowly. Tuberculosis is an infectious disease and quite common historically, often referred to as consumption in the past, as mentioned in the novels of Lu Xun. In modern times, tuberculosis is relatively manageable if the infection has not developed resistance to drugs. Proper anti-tuberculosis treatment can result in a cure rate exceeding 90% on the first attempt. However, if the treatment is not adhered to correctly—if the patient stops taking the medication prematurely or does not follow the prescribed regimen—the bacteria may develop resistance, reducing the effectiveness of the treatment. This is particularly problematic in elderly patients, who might also experience adverse reactions to tuberculosis medications, making treatment difficult. Thus, while tuberculosis is generally treatable, infections with drug-resistant strains can be fatal if not managed properly.

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Written by Yuan Lin Yan
Infectious Disease
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Is tuberculosis contagious?

Not all cases of tuberculosis are infectious. Some tuberculosis cases are infectious in the early stages but become non-infectious after proper treatment. Patients with open tuberculosis are highly contagious because their sputum contains tuberculosis bacilli. These bacilli can be released into the air through coughing, sneezing, laughing, or loud speaking, and can cause infection when inhaled by others. Some tuberculosis patients do not have detectable bacilli in their sputum, and their infectiousness is relatively much lower.

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Written by Wang Xiang Yu
Pulmonology
57sec home-news-image

Can you get tuberculosis on your own?

This question can be interpreted in two ways. First, whether every individual could potentially contract tuberculosis (TB) – to that, the answer is yes. Tuberculosis is a contagious disease, and we are all susceptible to the TB bacterium. Therefore, there is a chance, in our lifetimes, to be infected by the TB bacterium and consequently develop TB. The second interpretation revolves around whether a person could suddenly develop TB without specific reasons. Generally, this does not happen. In other words, a typical person would not contract TB unless they have been exposed to the TB bacterium. This means one does not contract TB arbitrarily; it occurs only after coming into contact with TB patients or the TB bacterium, leading to an infection in the lungs and resulting in TB.

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Written by Wang Xiang Yu
Pulmonology
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Symptoms of tuberculosis

Tuberculosis of the lung presents in many forms, as there are also various types of pulmonary tuberculosis, each exhibiting different symptoms. However, the most common symptoms primarily include coughing and expectoration, which are the most typical manifestations of pulmonary tuberculosis. The cough in pulmonary tuberculosis is generally mild, either dry or producing only a small amount of phlegm. If the tuberculosis is accompanied by cavities, the amount of phlegm may be larger. If there is a bacterial infection in addition to the tuberculosis, the phlegm may become purulent. Some patients with pulmonary tuberculosis may also experience hemoptysis, which can vary in amount from light to severe. A small number of patients may suffer from chest pain and difficulty breathing. Additionally, there are systemic symptoms associated with pulmonary tuberculosis, such as fever (both low and high fever may occur), night sweats, and fatigue, among others.

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Written by Wang Xiang Yu
Pulmonology
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How is tuberculosis transmitted?

How is pulmonary tuberculosis transmitted? First, we need to know the pathogen of pulmonary tuberculosis, which is the tuberculosis bacillus. Tuberculosis bacillus is a type of bacterium that can live in our surrounding environment. Pulmonary tuberculosis also needs a source of infection, that is, a patient carrying the tuberculosis bacillus. The most common source of tuberculosis infection is usually patients with secondary pulmonary tuberculosis. Then, its mode of transmission mainly includes coughing, sneezing, laughing, and talking loudly, which can release the tuberculosis bacilli from the patient into the air, spreading them through droplets. Droplet transmission is the most important route for the spread of pulmonary tuberculosis. Additionally, pulmonary tuberculosis can also be transmitted through other routes such as the gastrointestinal tract or the skin, although these methods of transmission are less common.

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Written by Wang Chun Mei
Pulmonology
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Does early-stage pulmonary tuberculosis cause fever?

Early stage tuberculosis patients generally exhibit clinical symptoms such as fever, primarily low-grade fever in the afternoon, along with coughing, hemoptysis, chest pain, chest tightness, and additional symptoms like weight loss, fatigue, and night sweats. These are very common and typical clinical symptoms of tuberculosis. Therefore, fever is very common in the early stages of tuberculosis. Consequently, once tuberculosis is accurately diagnosed in patients, it is crucial to promptly administer antitubercular drugs for systematic treatment. Usually, with a treatment duration of 6-9 months, the symptoms of early-stage tuberculosis and fever can be effectively controlled.