Transmission routes of viral hepatitis

Written by Xiong Hong Hai
Infectious Disease
Updated on February 11, 2025
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Different types of viral hepatitis are transmitted through different routes, and preventive measures should start from the cause of the disease, cutting off transmission routes and protecting susceptible individuals. Hepatitis A and E are mainly transmitted through the fecal-oral route, usually by consuming food or water contaminated with the hepatitis A or E virus. Hepatitis B and C, on the other hand, are mainly transmitted through blood, sexual contact, and from mother to child; general contact usually does not lead to infection. Preventive measures include cutting off transmission routes, such as avoiding contact with patients with viral hepatitis, and getting vaccinated against hepatitis B and A.

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Written by Xiong Hong Hai
Infectious Disease
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Transmission routes of viral hepatitis

Different types of viral hepatitis are transmitted through different routes, and preventive measures should start from the cause of the disease, cutting off transmission routes and protecting susceptible individuals. Hepatitis A and E are mainly transmitted through the fecal-oral route, usually by consuming food or water contaminated with the hepatitis A or E virus. Hepatitis B and C, on the other hand, are mainly transmitted through blood, sexual contact, and from mother to child; general contact usually does not lead to infection. Preventive measures include cutting off transmission routes, such as avoiding contact with patients with viral hepatitis, and getting vaccinated against hepatitis B and A.

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Written by Xiong Hong Hai
Infectious Disease
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Is viral hepatitis contagious?

Viral hepatitis is contagious, with different types of viral hepatitis transmitted in different ways. The common types of viral hepatitis include Hepatitis A, B, C, D, and E. Hepatitis A and E are acute self-limiting liver diseases, which are contagious during the symptomatic phase and also during the incubation period, primarily transmitted through the fecal-oral route via the digestive tract. Therefore, for those infected with Hepatitis A or E, gastrointestinal isolation and symptomatic treatment are required. Hepatitis B and C are transmitted through blood, sexual contact, and from mother to child, with general contact not leading to infection.

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Written by Xiong Hong Hai
Infectious Disease
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What are the indicators for viral hepatitis testing?

Viral hepatitis can be confirmed for infection through tests such as hepatitis B "two and a half pairs," hepatitis A antibodies, hepatitis C antibodies, and hepatitis E antibodies. By using the hepatitis B "two and a half pairs" test to look for the hepatitis B surface antigen, if the surface antigen is positive, it indicates infection with the hepatitis B virus. The hepatitis A antibody test primarily assesses for hepatitis A antibody IGM; if this is positive, it suggests an active infection. Through the hepatitis C antibody test, if positive, further testing for hepatitis C virus RNA can be conducted. The hepatitis E antibody test mainly looks at hepatitis E antibody IGM, and the interpretation should be based on the specific circumstances.

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Written by Ye Xi Yong
Infectious Diseases
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How is chronic viral hepatitis treated?

Chronic viral hepatitis is most commonly found in chronic hepatitis B and C, both of which have long disease courses and complex treatments, and some cases may even lead to lifelong infection. The key to their treatment actually lies in the timely initiation of standardized antiviral therapy. For hepatitis B, the antiviral treatment mainly includes interferon and nucleoside analogues, while the antiviral treatment for hepatitis C can also use interferon, as well as direct-acting antiviral drugs. The treatment for both diseases involves timely, standardized, and complete courses of antiviral therapy.

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Written by Zhang Jian Kang
Infectious Disease
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What are the symptoms of viral hepatitis?

Viral hepatitis primarily includes liver inflammation and damage caused by pathogens such as hepatitis A, B, C, E, etc. Their clinical symptoms are quite similar, mainly characterized by fatigue, poor appetite, nausea, vomiting, abdominal bloating after eating, jaundice, and dark urine. In cases of chronic liver diseases, such as chronic hepatitis caused by hepatitis B or C, if prolonged, it can also lead to facial features typical of liver disease, spider angiomas, and enlarged spleen. Once cirrhosis occurs, the patient may experience hepatic encephalopathy, gastrointestinal bleeding, abdominal distension with water accumulation, and significant abdominal tenderness. Thus, the symptoms of viral hepatitis relate to both the cause of the hepatitis and the type of hepatitis.