What are the symptoms when pulmonary embolism becomes severe?

Written by Yuan Qing
Pulmonology
Updated on December 02, 2024
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Pulmonary embolism can vary in severity, with serious cases primarily causing unstable vital signs. The disease primarily arises from venous thrombi in the venous system, which travel with the venous blood back to the right heart, and then with the blood flow from the right heart back to the aorta. If the thrombus is relatively large, it can easily become lodged in the pulmonary artery, forming a pulmonary embolism. The symptoms of pulmonary embolism can range from mild to severe. Based on the patient's symptoms and vital signs, pulmonary embolism is categorized into low risk, intermediate risk, and high risk. Low and intermediate risk typically indicate that the patient's vital signs are relatively stable, with normal blood pressure, heart rate, and pulse oximetry saturation. In severe cases, patients may exhibit noticeable symptoms such as coughing up blood, difficulty breathing, low blood pressure, shock, and oliguria. These represent the more severe cases of pulmonary embolism.

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Written by Wang Li Bing
Intensive Care Medicine Department
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What are the precursors of pulmonary embolism?

Pulmonary embolism is also relatively common in clinical practice. Its precursors may include varying degrees of respiratory difficulty, chest tightness, and shortness of breath, among others. If such symptoms occur, medical attention should be sought promptly, primarily to rule out the possibility of acute myocardial infarction. Pulmonary artery CTA can further confirm whether there is a pulmonary embolism. In cases of extensive pulmonary embolism, there is a high risk of sudden death, and aggressive thrombolytic and anticoagulation treatments should be administered. If the patient's chest tightness and shortness of breath are relieved after the aforementioned treatments, hospitalization for observation and treatment is still necessary.

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Written by Yuan Qing
Pulmonology
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Is it good to place a filter for pulmonary embolism or not?

Whether it is good or not to place a filter for pulmonary embolism mainly depends on the cause of the pulmonary embolism and whether there are indications for placing a filter. Generally speaking, if pulmonary embolism is caused by the formation of blood clots in the lower limbs or the inferior vena cava, placing a filter can generally be beneficial. However, not all cases of lower limb venous thrombosis require a filter. Filters are usually only used for deep or large vein thromboses that are not suitable for thrombectomy or thrombolysis treatments. If a filter is placed under other conditions, it is very likely that thrombosis will re-form on the surface of the filter, potentially leading to some recurrent pulmonary embolisms or iatrogenic pulmonary embolisms. Therefore, the decision to place a filter is complex and requires a doctor to weigh the pros and cons before deciding whether or not to proceed.

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Written by Yuan Qing
Pulmonology
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Why do patients with pulmonary embolism feel sleepy?

Patients with pulmonary embolism primarily suffer from emboli within the venous system, which travel back to the right heart and then become lodged in the pulmonary artery, forming a pulmonary artery thrombus. This reduces pulmonary blood flow and impacts the exchange of air in the lungs, leading to hypoxia in the patient. Following hypoxia, the brain tends to enter a sleepy state, thus many patients with pulmonary embolism exhibit sleepiness. This sleepiness is related to the pathophysiological mechanisms of pulmonary embolism. At this point, it is crucial to provide sufficient oxygen to the patient to address their hypoxemia. Ultimately, the most fundamental treatments are prompt thrombolysis or anticoagulation therapy to resolve the embolus, addressing the condition fundamentally.

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Written by Wei Shi Liang
Intensive Care Unit
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Is pulmonary embolism related to pneumonia?

If unexplained shortness of breath, pleuritic chest pain, tachycardia, and decreased oxygen saturation occur, one should be highly vigilant about pulmonary embolism. Generally, pulmonary embolism has no direct relationship with pneumonia. High-risk factors for pulmonary embolism include obesity, prolonged immobilization, stroke, congestive heart failure, malignant tumor, inflammatory bowel disease, lower limb fracture, anesthesia time exceeding 30 minutes, and acquired or genetic hypercoagulable state. It usually manifests as difficulty breathing, rapid breathing, and pleuritic chest pain.

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Written by An Yong Peng
Pulmonology
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How is pulmonary embolism caused in young people?

Common causes of pulmonary embolism in young people include the following aspects: First, fractures, especially fractures of the lower limbs, are prone to deep vein thrombosis and pulmonary embolism; Second, thrombophilia, some young people due to congenital genetic factors, which can lead to easy formation of blood clots in arteries or veins, and potentially increase the incidence of pulmonary embolism; Third, prolonged immobilization, such as long periods of sitting, can lead to slow blood flow in the lower limbs, which might result in deep vein thrombosis and pulmonary embolism; Fourth, other factors like severe infections could also trigger pulmonary embolism; furthermore, the risk of pulmonary embolism is also higher in pregnant women during the perinatal period.