How severe is an atrial septal defect considered to be?

Written by Li Hai Wen
Cardiology
Updated on September 11, 2024
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Atrial septal defect (ASD) is a relatively common congenital heart disease in clinical practice. From a medical perspective, the severity of ASD depends on whether the patient is an adult or a child. For adults with ASD, generally speaking, defects larger than 20 millimeters are considered large atrial septal defects, which are more severe. If the defect size is between 10 and 20 millimeters, it is often classified as a moderate atrial septal defect. Defects smaller than 4 millimeters are considered small atrial septal defects. Generally, small and moderate atrial septal defects are not severe. For children, an atrial septal defect larger than 10 millimeters is considered a large atrial septal defect, which is more severe. Sizes between 5 and 10 millimeters are classified as moderate atrial septal defects. Defects smaller than 5 millimeters are considered small atrial septal defects, which generally are not severe.

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Written by Tang Li
Cardiology
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What are the symptoms of an atrial septal defect?

Atrial septal defect is the most common congenital heart disease in adults, accounting for 20%-30% of adult congenital heart diseases, with a higher incidence in females than males, with a male to female ratio of about 1:1.5-3. There is also a familial tendency. Apart from larger defects, children with atrial septal defects generally show no symptoms. As they age, symptoms gradually appear, with exertional dyspnea being the main symptom, followed by supraventricular arrhythmias, especially atrial flutter and fibrillation, which exacerbate the symptoms. Some patients may develop right heart failure due to excessive right ventricular volume load. In the late stages, about 15% of patients develop severe pulmonary hypertension, resulting in a right-to-left shunt and cyanosis.

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Written by Li Hai Wen
Cardiology
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What does atrial septal defect mean?

Atrial septal defect is a relatively common type of congenital heart disease encountered clinically. In simple terms, the human heart has four chambers: the left atrium, right atrium, left ventricle, and right ventricle. Between the left and right atria, there is a structure called the atrial septum, which separates the two atria. If there is a hole in this septum, this condition is referred to as an atrial septal defect. Atrial septal defects are common congenital heart conditions, and when the defect is severe, it often accompanies heart failure and other complications. Under such circumstances, it is crucial to visit a cardiologist for a formal assessment to determine the necessity and approach to treatment.

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Written by Zhang Zhi Gong
Cardiothoracic Surgery
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The difference between ventricular septal defect and atrial septal defect

The difference between a ventricular septal defect and an atrial septal defect mainly lies in their locations. A normal heart is divided into four chambers, which are the left ventricle, right ventricle, left atrium, and right atrium. Each chamber is separated by a septum, much like walls between rooms in a house. Due to certain reasons, such as congenital heart defects, there may be openings or defects in these walls, known as septal defects. An atrial septal defect refers to a defect between the right atrium and the left atrium, whereas a ventricular septal defect pertains to a defect between the left and right ventricles. The murmur of atrial septal defects is relatively softer, as the pressure difference between the atria is smaller, and the defect is located higher up. In contrast, the murmur of ventricular septal defects is louder due to the greater pressure difference between the ventricles and is located lower down, approximately between the third and fourth ribs. The murmur of atrial septal defects is found between the second and third ribs. Moreover, since the pressure difference in ventricular septal defects is greater, the impact on the heart is relatively more significant.

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Written by Li Hai Wen
Cardiology
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Can atrial septal defect heal by itself?

Atrial septal defect is a relatively common congenital heart disease in infants and toddlers. It is indeed possible for a child's atrial septal defect to close on its own. Some atrial septal defects can close as the child grows. Depending on the severity, atrial septal defects can be categorized into small defects. Generally, if the defect is less than 5 millimeters, it is possible for the defect to close as the child develops. If it has not closed by the age of two, it generally will not close on its own thereafter.

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Can someone with an atrial septal defect get pregnant?

Whether patients with atrial septal defects can become pregnant depends on the following factors: 1. Whether the patient normally has symptoms. 2. Whether the echocardiography indicates heart enlargement or pulmonary hypertension. 3. The size of the atrial septal defect. 4. Whether there is a combination of arrhythmias such as atrial flutter or atrial fibrillation, and complications such as pulmonary hypertension or heart failure. For those without symptoms, and where the defect does not cause pulmonary hypertension or right heart enlargement, choosing to become pregnant is possible. Complications are not common in pregnant women with isolated atrial septal defects without pulmonary hypertension. Studies have shown that the incidence of complications in pregnant women, whether the defect is repaired or not, is relatively low. If the patient has related arrhythmias and complications, it should be closely monitored, because the cardiovascular system of the mother undergoes changes during pregnancy, leading to increased cardiac workload and a higher burden on the heart, which in turn can increase the incidence of arrhythmias. For women who are already at high risk of atrial flutter or fibrillation, this risk can increase further. Additionally, pregnant women are in an older physiological state, making it easier to form blood clots, and for those with atrial septal defects, the risk of paradoxical thrombosis increases.