Tetralogy of Fallot syncope causes

Written by Hu Qi Feng
Pediatrics
Updated on September 16, 2024
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The causes of syncope in Tetralogy of Fallot generally involve episodic hypoxia attacks, which are more common in infants. Triggers include breastfeeding, crying, emotional excitement, anemia, and infections. The symptoms manifest as episodic breathing difficulties, and severe cases can suddenly lead to syncope with convulsions or even death. The underlying reason is the narrowing of the pulmonary artery infundibulum accompanied by muscular spasms, causing obstruction of the pulmonary artery and intensifying cerebral hypoxia. Older children may complain of headaches and dizziness.

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Does Tetralogy of Fallot involve chromosomal abnormalities?

Tetralogy of Fallot is primarily a developmental disorder, generally unrelated to chromosomes, with no chromosomal abnormalities. The cause of the disease is still not very clear. If pregnant again and giving birth again, it generally does not recur. Therefore, couples undergoing chromosomal testing before pregnancy is a common practice. It is generally believed that the four malformations in Tetralogy of Fallot occur due to viral infections acquired by the fetus during pregnancy, the mother consuming alcohol, or the use of certain medications during pregnancy. Currently, these are considered related factors, and so far, no abnormalities have been found related to genetics or chromosomes.

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Tetralogy of Fallot in children who prefer squatting is because

Tetralogy of Fallot exhibits squatting symptoms because squatting involves flexing the lower limbs, which reduces the amount of venous return to the heart, thereby decreasing the cardiac workload. At the same time, the arteries of the lower limbs are compressed, increasing systemic vascular resistance, reducing right-to-left shunting, and temporarily alleviating hypoxia symptoms. Infants who cannot walk often prefer to be held with their thighs up, with both lower limbs bent; after they become able to walk, they frequently squat down momentarily during walking or playing.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot is what?

Tetralogy of Fallot is the most common cyanotic congenital heart disease in infants, accounting for about twelve percent of all congenital heart diseases. It was thoroughly described by the French physician Fallot in 1888, which is how it got its name. Tetralogy of Fallot consists of four cardiac malformations: first, obstruction of the right ventricular outflow tract; second, ventricular septal defect; third, overriding aorta; fourth, right ventricular hypertrophy.

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Written by Hu Qi Feng
Pediatrics
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The reason for squatting in Tetralogy of Fallot

The reason for squatting is that when squatting, the lower limbs are bent, which reduces the amount of blood returning to the heart through the veins, thereby reducing the load on the heart. At the same time, the arteries in the lower limbs are compressed, which increases the resistance in the systemic circulation and reduces the right-to-left shunt volume, allowing temporary relief from hypoxia symptoms. Babies who cannot walk often like to be held by adults in a position that bends the lower limbs to reduce the amount of blood returning to the heart. This frequently occurs during walking and playing, often characterized by brief periods of squatting.

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Written by Hu Qi Feng
Pediatrics
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Tetralogy of Fallot Emergency Measures

Generally, one should often drink water to prevent infection, prevent dehydration and complications. Infants and young children should be especially careful in their care, to avoid episodes of paroxysmal hypoxia. In mild cases of hypoxic episodes, placing them in a knee-chest position can alleviate the symptoms. In severe cases, oxygen should be administered immediately, along with the appropriate drug treatment. If the episodes cannot be effectively controlled with medication, emergency surgical intervention may be necessary. With the continuous improvement in surgical techniques this year, the mortality rate for curative surgeries has been decreasing.