What medicine to take for gastric ulcer?

Written by Jiang Guo Ming
Gastroenterology
Updated on September 04, 2024
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The stomach ulcers referred to here are generally benign gastric ulcers. The treatment plan should be determined based on whether there is a Helicobacter pylori infection. If there is no Helicobacter pylori infection, it is first important to develop good dietary and living habits, and then treat the symptoms, such as suppressing stomach acid, protecting the gastric mucosa, and increasing gastric motility. If there is a Helicobacter pylori infection, antibacterial treatment is needed. Typically, a triple or quadruple antibiotic therapy is used; a proton pump inhibitor plus two antibiotics constitute the triple therapy, and adding a bismuth agent constitutes the quadruple therapy. A course of treatment lasts for two weeks, which generally can eradicate the bacteria for a definitive cure. (Medications should be used under the guidance of a clinical doctor, according to specific conditions.)

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Written by Li Xue Qing
Gastroenterology
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Complications of gastric ulcers

The main complications of gastric ulcers are fourfold: one is upper gastrointestinal bleeding; the second is perforation; the third is pyloric obstruction; the fourth is malignant transformation. Upper gastrointestinal bleeding is the most common complication of gastric ulcers. If a patient has experienced bleeding, there is a high likelihood of recurrence. Perforations mainly occur in elderly individuals. Pyloric obstruction is primarily caused by ulcers in the pyloric canal and pre-pyloric area. It is divided into mechanical obstruction and functional obstruction. Mechanical obstruction results from scarring after the ulcer heals, which narrows the pyloric opening. Functional obstruction is due to congestion and edema of the mucosa after the ulcer, causing relative narrowing of the pylorus. As for malignant transformation, it is still controversial, but it is generally believed to be around 1%-7%.

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Written by Jiang Guo Ming
Gastroenterology
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How to treat bleeding from gastric ulcers?

If it is a mild gastric ulcer bleeding, it may only manifest as black stool without any obvious specific discomfort symptoms and stable vital signs. This condition can be managed by controlling the diet and appropriately taking or intravenously using proton pump inhibitors such as omeprazole, lansoprazole, etc., which often can be curative. If the bleeding is considerable, presenting symptoms like vomiting coffee-colored or dark red liquid, fainting, profuse sweating, blood pressure drop, etc., this condition requires timely hospital treatment. Medication primarily includes proton pump inhibitors combined with hemostatic drugs, nutritional support, prevention of complications, etc. If the medical treatment is ineffective, endoscopic hemostasis might be needed, and further more, surgical intervention may be considered.

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Written by Li Xue Qing
Gastroenterology
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How to treat gastric ulcers?

The treatment of gastric ulcers mainly consists of general management and pharmacotherapy. General management involves patients avoiding spicy, stimulating, and cold foods, eating regular meals, and avoiding medications that may harm the stomach, such as non-steroidal anti-inflammatory drugs. Pharmacotherapy mainly includes gastroprotective therapy and treatment against Helicobacter pylori. Gastroprotective therapy includes neutralizing stomach acid with agents such as magnesium carbonate chewing tablets, acid-suppressing medications like proton pump inhibitors and H2 receptor antagonists, pantoprazole, cimetidine, etc. Medications to protect the gastric mucosa, such as sucralfate, bismuth preparations, etc., are also used. Treatment against Helicobacter pylori mainly includes triple and quadruple therapy. Triple therapy involves a proton pump inhibitor or a bismuth agent combined with two types of antibiotics, and quadruple therapy consists of a proton pump inhibitor, a bismuth agent, and two types of antibiotics. Antibiotics commonly used include amoxicillin, clarithromycin, furazolidone, levofloxacin, metronidazole, tetracycline, etc. Treatment generally lasts seven to ten days, with overall therapy for gastric ulcers spanning about a month. (Please undertake any medication under the guidance of a doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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Can gastric ulcers be cured?

Gastric ulcers are classified into benign and malignant types. Most duodenal bulb ulcers and gastric ulcers are benign and can be cured through medication. Treatment plans are usually determined based on the presence of Helicobacter pylori infection. Patients with Helicobacter pylori infection can be treated with antibacterial therapy. If there is no infection, symptomatic treatment alone is generally sufficient for a cure. If the ulcer is malignant or is a giant ulcer, surgical treatment is generally required. For those who cannot undergo surgery, radiotherapy or chemotherapy may be needed. Generally, the prognosis for malignant ulcers is worse than for benign ulcers.

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Written by Ren Zheng Xin
Gastroenterology
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Is gastric ulcer contagious?

Gastric ulcers are lesions that occur in the gastric mucosa. Ulcer disease is not contagious, therefore it does not transmit from person to person. Most gastric ulcers are caused by an infection of Helicobacter pylori, which damages the protective barrier of the gastric mucosa, and ulcers arise under the stimulation of gastric acid. The principles of treatment mainly involve eradicating Helicobacter pylori, suppressing gastric acid secretion, and protecting the gastric mucosa. Additionally, dietary control is important, including eating more vegetables and fruits, consuming less spicy and irritating foods, and paying attention to regular and measured meal times.