The primary cause of rheumatic heart disease is an abnormal immune response caused by infection with hemolytic streptococcus, which leads to damage of the heart valves. This damage results in narrowing or insufficiency of the valves, altering the hemodynamics within the blood and increasing the burden on the heart, thereby causing a series of clinical symptoms. Early control of streptococcal infections can reduce the occurrence of rheumatic heart disease. Common streptococcal infections include upper respiratory tract infections, acute tonsillitis, and suppurative tonsillitis. Actively using effective antibiotics to control these infections can greatly reduce the incidence of rheumatic heart disease.