Heart Failure Drug Therapy

Written by Zhang Yue Mei
Cardiology
Updated on September 17, 2024
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Due to some myocardial diseases that cause damage to the myocardium, or other reasons that increase the heart's load, heart failure may occur. Clinical treatment involves strengthening the heart and promoting diuresis, improving blood vessel function, increasing the heart’s contractility, reducing the heart’s resistance, and decreasing the volume of blood returning to the heart. Through these effective drug treatments, heart failure can be corrected. Patients with heart failure should avoid excessive fatigue and maintain a low-salt diet to prevent increasing the burden on the heart.

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Written by Zhang Lu
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Can childbirth lead to heart failure?

Childbirth refers to the delivery of a fetus through vaginal delivery or cesarean section, and it represents a significant strain on a woman’s heart. Regardless of the type of delivery, there is a possibility of leading to heart failure to some extent. Especially during the second stage of labor, pregnant women often exert greater effort, significantly increasing the load on the heart. If there is poor heart function or pre-existing cardiac disease, it could lead to heart failure. In some cases, if the heart disease is severe and cannot withstand delivery, a cesarean section must be chosen. However, cesarean delivery can also lead to heart failure, mainly due to a large amount of blood flowing back to the peripheral circulation from the uterus after the fetus is delivered, causing a significant increase in the preload on the heart and easily leading to the onset of heart failure.

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What causes acute heart failure?

Acute heart failure can occur in diseases of the heart itself, as well as in other serious diseases that lead to heart failure. Common cardiac diseases include severe arrhythmias, cardiomyopathy, and myocardial infarction. If these diseases are not well treated, they can cause acute heart failure. Other diseases can be seen in cases such as drug poisoning, severe anemia, severe infection, and during the treatment of other diseases when excessive use of fluids increases the burden on the heart, leading to acute heart failure.

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Written by Wang Li Bing
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Why does heart failure cause ascites?

Heart failure is relatively common in clinical settings, primarily divided into left heart failure, right heart failure, and global heart failure. The clinical manifestations of left heart failure are mainly reflected in symptoms of pulmonary congestion. It can present as varying degrees of dyspnea, cough, expectoration, palpitations, and fatigue. Right heart failure is mainly due to obstruction of the inferior vena cava flow, leading to increased venous pressure and capillary pressure. This causes plasma components to extravasate and ultimately leads to the formation of ascites. Global heart failure includes the symptoms of both left and right heart failure. Therefore, it is essential to seek medical attention promptly after heart failure occurs.

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Written by Wei Shi Liang
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Causes of Acute Heart Failure

The main causes of acute heart failure include coronary heart disease, valvular disease, hypertension, and cardiomyopathies, such as toxic cardiomyopathy or hypothyroidism-related cardiomyopathy, as well as idiopathic cardiomyopathy. Myocarditis and arrhythmia-related causes can also lead to heart failure, but there are often triggers present clinically. Common triggers include poor treatment compliance, arrhythmias, anemia, infections, myocardial ischemia, excessive fluid intake, poor dietary control, and increased cardiac output, such as during strenuous activity and pregnancy, which can lead to increased cardiac output and cause heart failure. Conditions such as excessive fluid volume, hypertension, hyperthyroidism, and pulmonary embolism can also trigger heart failure.

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The basic mechanisms of heart failure

Heart failure is not an independent disease; it can be caused by various factors, such as myocardial infarction, cardiomyopathy, and various myocarditis, which lead to changes in the heart structure and subsequent cardiac dysfunction. Heart failure is mainly due to a disturbance in the heart's contractile function or diastolic function, which prevents the heart from adequately ejecting the returning blood volume. This results in pulmonary congestion, systemic circulation congestion, and a series of syndromes caused by insufficient arterial perfusion.