The difference between rheumatic fever and rheumatoid arthritis

Written by Yang Ya Meng
Rheumatology
Updated on September 24, 2024
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Patients with rheumatoid arthritis primarily exhibit symmetrical swelling and pain in the small joints of both hands as the main clinical manifestations, with rarely any involvement of visceral organs. Blood tests can show elevated inflammatory markers, erythrocyte sedimentation rate (ESR), C-reactive protein, as well as positive rheumatoid factor, anti-CCP antibodies, and AK antibodies. These indicators can be considered as diagnostic for rheumatoid arthritis. Patients with rheumatic fever, in addition to joint pain, often have cardiac complications, such as mitral stenosis or chorea-like symptoms. The main difference between rheumatic fever and internal rheumatism is that patients with rheumatic fever often have cardiac complications.

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Written by Yang Ya Meng
Rheumatology
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Treatment of acute rheumatic fever

The treatment of rheumatic fever includes general treatment, where patients are advised to rest in bed. The second is the use of antibiotics, aimed at eliminating streptococcal infections to prevent recurrent attacks of rheumatic fever. The third is anti-rheumatic treatment, with the preferred choice being non-steroidal anti-inflammatory drugs, such as sustained-release diclofenac sodium tablets. If the patient's rheumatic fever affects the heart, corticosteroid treatment is also required. In addition, to assist in the reduction of corticosteroids, some immunosuppressants need to be added, such as methotrexate and leflunomide, which help control the condition. For the treatment of complications of rheumatic disease, such as concurrent lung infection, antibiotic treatment should also be considered. (The use of medication should be under the guidance of a professional doctor.)

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Written by Li Jing
Rheumatology
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Does rheumatic fever spread?

Firstly, rheumatic fever is a group of delayed sequelae caused by an infection of Group A Streptococci, simply put, it refers to a type of reactive arthritis that appears after an upper respiratory tract infection. It is associated with this streptococcus, and mostly occurs during the cold and humid seasons of winter and spring. It can affect people of any age, but is most commonly seen in children aged 5-14 and adolescents. Therefore, it is not a contagious disease, but rather a set of symptoms, such as fever and joint pain, appearing in individuals with weakened immune systems following an upper respiratory tract infection. Some people may even experience valvular heart disease. However, if treated actively in the early stages, the disease usually does not lead to any long-term consequences, unless it goes untreated or is treated under poor medical conditions, which may then result in rheumatic arthritis and rheumatic heart disease.

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Written by Yang Ya Meng
Rheumatology
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Symptoms of recurrent rheumatic fever

Symptoms of recurrent rheumatic fever in the early stages may include fever and sore throat, similar to streptococcal infections. Later, patients may experience joint pain, some may develop ring-shaped erythema on the skin, and others may develop subcutaneous nodules. Severe cases may even exhibit symptoms such as carditis and chorea. If a previous rheumatic fever patient shows these symptoms, the possibility of recurrence should be considered. Treatment involves using antibiotics to eliminate streptococcal infections. Additionally, anti-inflammatory pain relievers should be used to manage joint pain. In severe cases, such as those with cardiac inflammation, corticosteroids may also be considered. (Please use medication under the guidance of a physician.)

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Written by Yang Ya Meng
Rheumatology
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What tests are needed for rheumatic fever?

The examinations for rheumatic fever include laboratory tests and electrocardiograms, as well as imaging studies. Laboratory tests include indicators of streptococcal infection, commonly using throat swab bacterial cultures, which have a positivity rate of about 20% to 25%. They also include anti-streptolysin O tests, generally considered positive if the titer is above 1:400. Secondly, the tests include those for acute inflammatory response, common markers of which are elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Electrocardiograms help in detecting various arrhythmias, such as sinus tachycardia and prolonged PR interval. Echocardiography can be used to detect any abnormalities in the mitral valve of the heart.

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Written by Yang Ya Meng
Rheumatology
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The Difference Between Rheumatic Fever and Rheumatoid Arthritis

Most patients with rheumatoid arthritis primarily exhibit symptoms related to the joints. Mainly affected are the symmetrical small joints of both hands, including both wrists, both palmar digital joints, and both proximal interphalangeal joints. In addition, patients with rheumatoid arthritis often have elevated rheumatoid factor, anti-CCP antibodies, and AKA antibodies. During the acute phase of joint disease, there is a marked increase in inflammatory markers, which is a major manifestation of rheumatoid arthritis. Patients with rheumatic fever, aside from joint pain, may also have heart valve disorders, such as mitral stenosis, and some patients may develop skin lesions, commonly erythema nodosum. Most importantly, patients with rheumatic conditions often show a significant increase in anti-streptolysin O.