Tetralogy of Fallot

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Written by Yao Li Qin
Pediatrics
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Tetralogy of Fallot surgery success rate

Tetralogy of Fallot is a common cyanotic congenital heart disease in children after the age of one. It consists of four abnormalities: ventricular septal defect, obstruction of the right ventricular outflow tract, overriding aorta, and right ventricular hypertrophy. Once Tetralogy of Fallot is diagnosed, the ultimate treatment is surgical. With the development of pediatric cardiothoracic surgery, there are no specific requirements regarding the birth month or weight of the child for the surgery, so the success rate of Tetralogy of Fallot surgery is now very high. If a child has Tetralogy of Fallot, it is crucial to seek active treatment and not to give up.

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Written by Chen Guang Yin
Cardiology
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Is it normal after the complete repair of Tetralogy of Fallot?

Tetralogy of Fallot is a serious congenital heart defect characterized by a ventricular septal defect, pulmonary stenosis, and problems with right ventricular obstruction. It is a congenital disease that can cause hypoxia throughout the body, especially as age increases, the symptoms tend to worsen. After the corrective surgery for Tetralogy of Fallot, it does not mean that the patient is completely normal. Their lifespan is still somewhat impacted. They will not be like patients with simpler congenital heart diseases such as only a ventricular septal defect or atrial septal defect, who can achieve a natural lifespan. For these individuals, their lifespan is still impacted to some extent. As they age post-surgery, some complications may arise, including sudden death, and some may require a second surgery.

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Written by Yan Xin Liang
Pediatrics
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The main cause of hypoxic attacks in Tetralogy of Fallot

Tetralogy of Fallot is a complex congenital heart disease, characterized by ventricular septal defect, right ventricular outflow tract obstruction, aorta overriding, and right ventricular hypertrophy. When the obstruction of the right ventricular outflow tract is severe, pulmonary artery blood flow significantly decreases. A large amount of unoxygenated venous blood passes through the ventricular septal defect causing a right-to-left shunt, which clinically manifests as severe cyanosis and increased red blood cells, and different degrees of hypoxia in the systemic circulation. Factors that can induce hypoxic episodes in these infants include feeding, crying, emotional agitation, anemia, infection, etc. These can suddenly lead to fainting, convulsions, or even death. The main reason is generally due to a sudden muscle spasm at the narrow pulmonary artery infundibulum on top of pre-existing stenosis, causing temporary pulmonary artery obstruction and exacerbating cerebral hypoxia, thus leading to severe hypoxic attacks.

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Written by Tong Peng
Pediatrics
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Does Tetralogy of Fallot easily lead to heart failure?

Tetralogy of Fallot often leads to symptoms of heart failure because it is a severe congenital disease. Affected children tend to present with cyanosis of the lips, impaired growth and development, and a simple echocardiography can reveal specific indicators such as aorta overriding, pulmonary stenosis, right ventricular hypertrophy, and ventricular septal defect. These children have limited lung and heart function, making them prone to increased cardiac load and symptoms of heart failure following infections or physical activity. Therefore, early surgical treatment is necessary for these children to prevent recurrent infectious diseases and heart failure, which can affect their normal growth and development. Additionally, it is crucial to enhance nutrition and exercise in their daily lives to boost their immune system. For Tetralogy of Fallot, early detection and treatment are essential.

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Written by Yan Xin Liang
Pediatrics
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Is tetralogy of Fallot a chromosomal problem?

Tetralogy of Fallot is the most common cyanotic congenital heart disease in childhood, consisting of four defects: ventricular septal defect, obstruction of the right ventricular outflow tract, overriding aorta, and right ventricular hypertrophy. It is a type of congenital heart disease, which generally stems from abnormal cardiovascular development during fetal life, resulting in cardiovascular malformations not controlled by chromosomes. The malformation of the cardiovascular system is mainly caused by genetic factors, environmental factors, and their interactions. The exact cause of this congenital heart disease has not been fully identified yet, indicating that it is not a chromosomal disease but a result of cardiovascular developmental abnormalities during fetal life.

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Written by Chen Guang Yin
Cardiology
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Can Tetralogy of Fallot receive oxygen therapy?

Tetralogy of Fallot is a congenital heart defect that includes abnormalities such as ventricular septal defects, pulmonary valve stenosis, and stenosis of the right ventricular outflow tract. Due to these congenital defects, the ejection of blood from the heart is affected, which in turn impacts the blood supply to various systems and organs throughout the body. The patient may exhibit symptoms of cyanosis and hypoxia, especially after physical activity, hence the use of supplemental oxygen is advisable. While oxygen therapy can temporarily alleviate these hypoxic symptoms, it does not address the underlying issue. Surgery is necessary for a definitive resolution.

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Written by Chen Guang Yin
Cardiology
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Does Tetralogy of Fallot involve chromosomal abnormalities?

Tetralogy of Fallot is primarily a developmental disorder, generally unrelated to chromosomes, with no chromosomal abnormalities. The cause of the disease is still not very clear. If pregnant again and giving birth again, it generally does not recur. Therefore, couples undergoing chromosomal testing before pregnancy is a common practice. It is generally believed that the four malformations in Tetralogy of Fallot occur due to viral infections acquired by the fetus during pregnancy, the mother consuming alcohol, or the use of certain medications during pregnancy. Currently, these are considered related factors, and so far, no abnormalities have been found related to genetics or chromosomes.

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Written by Yao Li Qin
Pediatrics
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Can Tetralogy of Fallot be cured?

Tetralogy of Fallot is a type of congenital heart disease linked to family genetics and is considered quite severe among congenital heart conditions. Generally, within a few months after birth, children will exhibit cyanosis of the skin. It is crucial to perform surgery on the child promptly in such cases. Currently, the level of pediatric cardiothoracic surgery in our country has developed very rapidly. For typical cases of Tetralogy of Fallot, surgical treatment can be curative. Moreover, there are no specific requirements regarding weight and age for children undergoing heart surgery nowadays. Therefore, once Tetralogy of Fallot is diagnosed in young children, it is best to perform surgery as soon as possible. These children can then grow up, develop normally, and attend school like their peers.

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Written by Yao Li Qin
Pediatrics
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Can children with Tetralogy of Fallot be desired?

Tetralogy of Fallot is a relatively severe congenital heart disease. If it is detected during the fetal period, it is not an indication for termination of pregnancy. In other words, one should not choose to not have the baby simply because it has Tetralogy of Fallot. However, it is crucial that the baby undergoes a timely echocardiogram after birth to assess the condition and undergo surgery as soon as possible. Currently, pediatric surgery, particularly cardiothoracic surgery, is developing very rapidly in our country. With multiple surgeries, Tetralogy of Fallot can be surgically cured. Therefore, having a child with Tetralogy of Fallot is not an indication for termination of pregnancy.

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Written by Yao Li Qin
Pediatrics
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Tetralogy of Fallot electrocardiogram manifestations

Tetralogy of Fallot is a common type of cyanotic congenital heart disease, primarily composed of four structural components: first, a ventricular septal defect; second, an overriding aorta; third, hypertrophy of the right ventricle; and fourth, obstruction of the right ventricular outflow tract. When performing an electrocardiogram (ECG) on Tetralogy of Fallot, it often shows right ventricular hypertrophy, and can also display right atrial hypertrophy. Initially, there may be hypertrophy of both the left and right ventricles. As the child develops cyanosis, it progressively evolves into hypertrophy of the right ventricle. These are the typical ECG findings in Tetralogy of Fallot.