Tetanus


What are the situations for tetanus shots?
Objects carrying tetanus bacillus, or tissues damaged by animals, require tetanus vaccination to prevent tetanus, such as rusty nails, animal claws, animal bites, venomous snake bites, and wounds contaminated by dirt can easily lead to infection by tetanus bacillus. Tetanus is a possible condition, so after an injury, it is necessary to immediately rinse the wound with soap and water or running water to wash away the toxins, which helps reduce the chance of infection. Then thoroughly disinfect the wound with iodophor, which can also reduce infection, and go to the hospital to receive tetanus antitoxin or tetanus immunoglobulin within 24 hours to prevent the onset of tetanus. The incubation period for tetanus is generally three to seven days, but it can be longer, so it is advised to go to the hospital for an injection as soon as possible after injury, to prevent the onset of the disease and avoid serious events.


How long does it take for tetanus to develop?
Tetanus is an acute, specific infection caused by the invasion of Clostridium tetani into a human wound, where it grows and reproduces, producing toxins. Tetanus is a Gram-positive, anaerobic, spore-forming bacillus that is widely present in the external environment. Tetanus occurs only when tetanus bacillus grows and reproduces locally in a wound and produces exotoxins, which are the cause of the disease. The toxins of tetanus include spasm toxin and hemolysin. The incubation period of tetanus generally ranges from six to ten days. In some cases, it can occur within 24 hours or take as long as 20 to 30 days, or even months, particularly following the removal of foreign bodies or shrapnel. Neonatal tetanus generally occurs seven days after umbilical cord separation, clinically also known as the "seven-day wind." Generally, the shorter the duration of the incubation period or prodromal symptoms, the more severe the symptoms and the higher the mortality rate.


Is tetanus easy to infect?
Tetanus is not easily contracted.Tetanus bacilli belong to anaerobes, and are prone to occur in conditions where the wounds are deep, in an anoxic or low oxygen situation, heavily contaminated wounds such as with dirt or rust, and in cases of open fractures with large wounds. In these situations, tetanus bacilli can colonize the skin and mucous membranes, producing neurotoxins that lead to a series of complications. Therefore, anti-tetanus treatment must be conducted for wounds in an anaerobic environment, such as heavily arsenic-contaminated wounds.For routine wounds that are shallow and small, it is sufficient to change the dressing.


There are several types of tetanus shots.
Tetanus injections are generally of two types, one being tetanus antitoxin and the other is human tetanus immunoglobulin. Tetanus antitoxin, which is more commonly used in our country, is a heterologous protein prepared from horse serum, making it relatively easy to obtain. However, an allergy test is needed for its use and it is widely used in our country at present. Tetanus immunoglobulin, though an ideal medication, is more complex to prepare. Its production is complicated and limited in our country, thus it is not very widely used. Therefore, tetanus antitoxin is more broadly applied.


What are the symptoms of tetanus sequelae?
Tetanus, a viral infection problem, is actually quite a common disease. Usually, if the wound is deep or caused by rusty metals, there is a higher possibility of it leading to a tetanus infection. This condition requires timely treatment or prevention, otherwise, it can easily lead to complications. For example, tetanus typically causes complications primarily related to the lungs, such as pneumonia and pulmonary edema, among other issues, which are quite typical. The infected individual may experience symptoms such as difficulty breathing, coughing, nausea, etc., all of which could be a result of tetanus bacteria infection. In the case of a deep wound, it is crucial to promptly administer a vaccine to prevent exacerbation of the infection, and local treatment should be performed to effectively prevent it.


Is tetanus an anaerobic bacterium?
Tetanus is a specific infection often associated with trauma. In addition to various traumas, it can also occur in parturient women and newborns under unsanitary conditions. The pathogen is Clostridium tetani, an obligate anaerobe that stains positive under Gram staining conditions. Normally present in the intestines of humans and animals, it is distributed in nature and common in soil. This type of bacteria has strong resistance to environmental conditions and can withstand boiling.


Can I breastfeed after getting a tetanus shot?
Current research indicates that lactating women are not contraindicated for tetanus vaccination; the main contraindication is allergy to the tetanus vaccine. Generally, if there are high-risk factors for tetanus infection, timely wound debridement and care should be performed, followed by early administration of passive immunization with tetanus vaccine. Generally, tetanus antitoxin can be used based on the results of a skin test. If the skin test result is strongly positive, its use should be avoided, and tetanus immunoglobulin should be chosen instead. The effective metabolic period of tetanus immunoglobulin is about three weeks. If high-risk factors for infection still exist beyond this time limit, timely enhancement of immune therapy should be considered. Regarding the tetanus vaccine, it is generally advised that the earlier it is administered, the better, as early administration can neutralize the tetanus toxin already present in the blood. However, if the tetanus toxin has already bound to nerve cells, treatment becomes relatively difficult.


How is tetanus diagnosed?
The diagnosis of tetanus requires comprehensive consideration. If the patient has a history of trauma with skin or mucosal wounds, and shows signs of muscle spasms, such as difficulty opening the mouth, stiffening of the neck, and increased reflexes, the possibility of a tetanus infection should be considered. Further, a culture of the wound can be conducted to see if Clostridium tetani can be cultured. If the culture is positive, a definitive diagnosis can be made. Additionally, tetanus needs to be differentiated from other diseases such as purulent meningitis, rabies, epilepsy, hysteria, and so on.


Which department do I go to for a tetanus shot?
Tetanus shots are widely used clinically, and patients generally receive the injection after sustaining an injury. Therefore, it is recommended that patients visit the surgical department. If at a community hospital, they should go to the surgical outpatient clinic. If in a secondary or tertiary hospital, patients can go to the surgical outpatient clinic or the emergency surgery department for treatment. After wound treatment, they can receive a tetanus shot as required. Thus, patients usually go to the surgical department or emergency surgery for the tetanus injection.


Can tetanus be cured?
Tetanus has a high mortality rate from infection, but it is not incurable. Even in primitive tribes in Africa, as long as the patient can survive the initial complications such as respiratory muscle spasms leading to suffocation, heart failure, lung infections, etc., they may be lucky to survive. However, in our daily lives today, if we accidentally sustain skin injuries or abrasions, we must not take them lightly and should head to the hospital to follow the doctor's advice. If a tetanus antitoxin injection is needed, it must be administered. Do not neglect it due to inconvenience, as it may lead to severe consequences. The initial symptoms of tetanus might include general weakness, muscle soreness, and spasms of the chewing muscles, which can later lead to severe muscle contractions and forceful spasms throughout the body. The patient remains fully conscious and can painfully experience the disease. Most patients may die from complications such as respiratory muscle spasms, suffocation, heart failure, and lung infections.