Encephalitis


Can encephalitis recur?
Encephalitis comes in various types, some of which are prone to recurrence, while others are monophasic and do not recur. The most common type is viral encephalitis, particularly infections caused by the herpes simplex virus. Although recovery from viral encephalitis after antiviral treatment is possible, it may leave some sequelae, but generally does not recur. Tuberculous meningoencephalitis, however, has a higher rate of recurrence, often related to the resistance of tuberculosis bacteria and inadequate anti-tuberculosis treatment. Patients need repeated lumbar puncture tests to confirm that the cerebrospinal fluid has returned to normal levels and require long-term use of anti-tuberculosis medications. Bacterial meningitis generally does not recur. Additionally, there are some autoimmune types of encephalitis, such as autoimmune encephalitis, multiple sclerosis, and neuromyelitis optica, where recurrence is possible when involving the brain.


What to do with pediatric encephalitis
If a child develops encephalitis, it is definitely recommended that they be hospitalized for treatment. It is necessary to assess their condition and determine the cause of the encephalitis: is it viral? Bacterial? Or caused by other pathogens? If encephalitis occurs, aggressive treatment is certainly required. In such cases, if the child is discharged from the hospital, they must regularly revisit the hospital for follow-up examinations, and the development of the child's nervous system must be monitored, focusing on motor and cognitive development. Regular assessments at the hospital are definitely required.


Symptoms of baby encephalitis
Generally speaking, the symptoms of encephalitis in babies usually start with fever. Encephalitis is an infectious disease, and the majority of cases present with fever, which could be either high or low. Next is vomiting. Since small infants cannot express headache, they usually manifest symptoms through crying, irritability, and restlessness. Additionally, there might be lethargy and malaise. Some may experience seizures, and others might have stiff neck, characterized by rigidity of the neck and changes in muscle tone of the limbs, among other symptoms. These are all symptoms of encephalitis.


How is encephalitis transmitted?
The commonly mentioned encephalitis is mainly caused by viral infections. There are many types of viruses that can cause encephalitis, including the more severe herpes simplex virus, varicella-zoster virus, etc. There are also some enteroviruses, like Coxsackie virus, and some adenoviruses. Typically, the transmission of encephalitis can occur via the fecal-oral route, where some enteroviruses enter the digestive tract through this route, then from the cells of the digestive tract to the bloodstream, and from there to the brain. Additionally, some viruses are transmitted through blood contact. For instance, if a patient has blisters that rupture and release a large amount of virus, and another person's blood comes into contact with these fluids, transmission can occur via blood. Generally, encephalitis is primarily transmitted through fecal-oral routes and bloodborne transmission.


Does encephalitis require hospitalization?
The severity of encephalitis can vary greatly; it is generally caused by viral infection. Among these viruses, Herpes Simplex Virus (HSV) is particularly dangerous. Encephalitis caused by HSV can be very severe, with symptoms including high fever, headache, nausea, vomiting, and other serious manifestations. Some patients may even experience seizures, coma, cognitive decline, and changes in mood and behavior. This type of encephalitis is very severe and definitely requires hospitalization. Typically, hospitalization lasts about 2 to 3 weeks, and proper antiviral treatment is necessary. Additionally, there are other forms of encephalitis caused by different viruses that are relatively milder and may even have a certain degree of self-healing properties. Generally, resting well, drinking plenty of water, and consuming fresh vegetables and fruits can lead to recovery. Therefore, whether hospitalization is necessary for encephalitis depends on the severity of the condition and the assessment of which virus has caused the infection. It cannot be generalized.


How is encephalitis diagnosed?
The diagnosis of encephalitis relies on the following aspects. First, it is based on clinical manifestations. If the patient clearly exhibits symptoms such as headache, fever, nausea, vomiting, and signs of increased intracranial pressure, and physical examination shows positive signs of meningeal irritation, then there is a high suspicion of encephalitis. Second, various auxiliary tests can be conducted. Initially non-invasive tests such as electroencephalograms (EEG) and magnetic resonance imaging (MRI) of the skull can be completed. If the MRI reveals significant abnormalities, such as abnormal signals in the frontal and temporal lobes including the hippocampus, then viral encephalitis should be highly suspected. If the EEG shows moderate abnormalities or increased slow waves, it also indicates damage to the cerebral cortex, serving as an indirect indicator of encephalitis. Third, a lumbar puncture can be performed to ascertain any abnormalities in the cerebrospinal fluid (CSF) routine and biochemical tests. If the cell count is elevated beyond ten times the normal value, an inflammatory infection is considered. There is often a minor to moderate increase in protein. The levels of glucose and chloride may decrease in bacterial and tuberculous encephalitis, while they are generally normal in viral encephalitis.


Can encephalitis be cured?
The viruses that cause encephalitis are relatively common. Whether they can be cured depends mainly on the type of virus causing the encephalitis, the severity of the condition, and whether the treatment is timely. Generally, most cases of encephalitis, such as those caused by enterovirus infections, tend to self-heal to a certain extent. The focus should be on care to prevent complications, electrolyte disorders, overheating, and to provide appropriate antiviral treatment. Most patients can be cured. However, there are also some more dangerous types of encephalitis, such as encephalitis caused by the type B encephalitis virus, which can rapidly lead to disturbances in consciousness, seizures, and even respiratory involvement, resulting in respiratory failure. This type of encephalitis is more severe and can leave significant sequelae even if successfully treated. For herpes simplex virus encephalitis, as long as the initial symptoms are not particularly severe and antiviral medications are used in a timely manner, the prognosis is still good.


How is encephalitis caused?
Encephalitis generally occurs when pathogens invade the central nervous system of the brain, resulting in corresponding clinical manifestations. Patients may exhibit symptoms such as headache, fever, nausea, vomiting, and even paralysis of limbs and cognitive impairments. Patients become confused, with reduced computational and comprehension abilities. Some may also exhibit psychiatric symptoms and even experience seizures and other manifestations of epilepsy. Encephalitis is caused by pathogens, commonly viruses. Viral infections that lead to what is known as viral encephalitis can spread through the bloodstream to the brain and cause illness. Additionally, bacterial infections can also cause encephalitis. There are mainly two routes for bacterial infections: one is through bloodstream transmission leading to inflammation of the nervous system, and the other can occur directly, for example, from inflammation of the mastoids, tonsils, or cavernous sinus, where bacteria directly invade the brain, leading to the respective clinical manifestations. Furthermore, tuberculosis can also infect and cause tuberculous encephalitis, meningitis, and similar conditions.


What are the symptoms of encephalitis?
The clinical manifestations of encephalitis are complex and varied, primarily caused by infections from pathogens such as viruses and bacteria. There are numerous clinical symptoms, with fever being quite common; patients generally exhibit significant fevers, which can reach up to 38 degrees Celsius or even as high as 40 degrees Celsius. Headache is also a very common clinical manifestation of encephalitis, with some patients experiencing severe headaches accompanied by pronounced nausea and vomiting. Additionally, some patients may exhibit psychiatric symptoms, which mainly include incoherent speech, hallucinations, and failing to recognize family members. Some patients may experience cognitive impairments, such as diminished memory, and significant deficits in computational and judgment abilities. In severe cases, some patients may have epileptic seizures, characterized by convulsions of the limbs. Overall, the manifestations of encephalitis are diverse and can range from simple fever and headache to severe conditions such as psychiatric symptoms, cognitive impairments, and epilepsy.


Is the blood count high in encephalitis?
Not all cases of encephalitis show an increase in blood counts. Elevated blood counts in encephalitis generally occur in bacterial infections, such as the most common pyogenic meningitis. This can cause a significant increase in blood counts, predominantly with neutrophils. Tuberculous meningitis can also show elevated blood counts, but not as prominently as pyogenic meningitis. In cases of viral infection, such as the common herpes simplex virus infection, patients might experience a decrease in blood counts. This is characterized by a reduction in the total number of white blood cells, a lower proportion of neutrophils, and a possible increase in lymphocyte proportion. If the patient has a concurrent lung infection or other bacterial infections at different sites, there might be an increase in blood counts, which can mask the blood abnormalities originally caused by the viral infection.