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Yan Chun
Oncology
About me
Graduated from the Clinical Medicine Department of Qingdao Medical College, has been working in the Oncology Department since 2001, obtained the qualification of attending physician in the same year. Promoted to attending physician in 2003. Qualified as associate chief physician in 2011. Participated in advanced studies at Jinan Cancer Hospital from June to November 2015. Serves as a youth member of the Chemical Therapy Committee in Shandong Province, youth member of the Elderly Therapy Committee of the Qingdao Anti-cancer Association, and a member of the Biologic Therapy Committee of the Qingdao Anti-cancer Association.
Proficient in diseases
Chemotherapy, radiotherapy, deep hyperthermia, targeted therapy, and endocrine therapy for various tumors such as stomach cancer, colorectal cancer, lung cancer, breast cancer, ovarian cancer, and pancreatic cancer.
Voices
Does liver cancer cause nosebleeds in its early stages?
Patients with early-stage liver cancer generally do not exhibit clinical symptoms of nosebleeds. Nosebleeds are a clinical manifestation of late-stage liver cancer. Early-stage liver cancer patients usually have atypical symptoms, which may include tenderness in the liver area, decreased appetite, abdominal bloating, and symptoms of indigestion. As the disease progresses, the liver cancer invades surrounding tissues and metastasizes to distant sites, leading to liver function impairment and coagulation disorders, which can result in nosebleeds. Some patients may also develop splenic hyperfunction due to liver damage, leading to a decrease in platelets, which can also cause nosebleeds. Additionally, some patients in the late stages may develop disseminated intravascular coagulation, leading to spontaneous internal and mucosal bleeding, clinically manifesting as nosebleeds.
How to distinguish between anal fissure and rectal cancer causing rectal bleeding
In clinical practice, to differentiate between rectal bleeding caused by anal fissures and that caused by rectal cancer, we can consider the following aspects. Firstly, rectal bleeding caused by anal fissures is generally accompanied by pain in the anal area, and the bleeding is especially severe after defecation, with blood attached to the surface of the stool. In contrast, rectal bleeding caused by rectal cancer rarely accompanies pain in the anal area, and the blood is generally mixed with the stool. Secondly, rectal bleeding from anal fissures is usually due to hard stools, and improving the condition of hard stools, along with providing local anti-inflammatory treatment, usually relieves the symptoms of bleeding. However, in the case of rectal cancer, besides hard stools, patients may also experience an increase in the frequency of defecation and signs of diarrhea, and typical anti-inflammatory treatments are not notably effective.
What are the symptoms on the face in the early stages of liver cancer?
In early-stage liver cancer patients, symptoms generally do not appear on their faces. This is because the tumors in early liver cancer are small, the lesions are localized, with shallow infiltration, no invasion of surrounding tissues or metastasis to distant organs, and thus, less damage to liver cells. Therefore, most cases do not show obvious symptoms clinically. Only when the lesions progress further do symptoms of disease dissemination appear in patients. These symptoms include persistent pain in the liver area, a significant decrease in appetite, fatigue, fever, and weight loss. Some patients may also experience symptoms of metastatic lesions, such as pain in bone metastases, headache, vomiting, hemiplegia, and aphasia in brain metastases, and cough, breathing difficulties, and chest pain in lung metastases.
Five Early Symptoms of Pancreatic Cancer
The five major symptoms of early pancreatic cancer patients include abdominal pain, jaundice, abdominal distension, diarrhea, fatigue, and more, among which the occurrence of abdominal pain is higher. Many patients with early pancreatic cancer experience persistent and hidden abdominal pain without other clinical symptoms, which often leads to missed opportunities for early diagnosis; Secondly, jaundice is also a main manifestation of early pancreatic cancer, particularly in the head of the pancreas, mainly due to the tumor causing obstructive jaundice; Thirdly, abdominal distension, which is generally a mild distension and often does not significantly attract clinical attention; Fourthly, patients often feel a general fatigue, which is difficult to alleviate with ordinary treatment methods; Lastly, diarrhea, which is often due to abnormal secretion of digestive fluids caused by the pathology, leading to diarrhea.
Early symptoms and signs of pancreatic cancer
Pancreatic cancer is a malignant tumor of the digestive system and does not have a high clinical incidence rate. Early symptoms of pancreatic cancer are not typical; some patients experience abdominal pain, primarily a persistent episodic pain that may radiate to the shoulder and back. Additionally, early-stage pancreatic head cancer patients may exhibit jaundice, often caused by obstructive jaundice due to tumor compression. Besides this, patients may also have clay-colored stools or urine the color of strong tea. Beyond these symptoms, early-stage patients exhibit no other signs. When typical clinical manifestations occur, they are generally indicative of mid to late-stage pancreatic cancer. Precursors to pancreatic cancer include persistent hidden pain in the shoulder or a stiff pain in the back. This continuous pain, often caused by the invasion of the abdominal nervous plexus, results in radiating pain.
How is pancreatic cancer caused?
Currently, there is no consensus in clinical practice regarding the causes of pancreatic cancer, but some studies have found that certain factors contribute to its high incidence. For example, patients with diabetes have a higher incidence of pancreatic cancer compared to those without diabetes, and having chronic pancreatitis and other diseases also leads to a higher occurrence of pancreatic cancer. Additionally, factors such as genetic mutations are also associated with the development of pancreatic cancer. Some research has found that there is a certain correlation between genetic factors and the occurrence of pancreatic cancer. Once pancreatic cancer develops, it leads to a variety of symptoms in clinical settings.
Can a cystic lesion in the liver be liver cancer?
Clinically, cystic lesions in the liver are mostly not liver cancer lesions, because liver cancer is a malignant tumor occurring in the liver. Clinically, on imaging, it is mainly manifested as occupying lesions in the liver, appearing as multiple hepatic nodules fused into a mass, or as a huge single nodular lesion. These lesions generally appear as solid lesions. When the tumor is large, ischemic necrosis can occur due to insufficient blood supply to the central area, resulting in cystic changes in the central region of the solid lesion. Therefore, some patients with large liver cancer may have cystic and solid lesions on imaging, but in most cases, liver cancer lesions are solid.
Does pancreatic cancer cause bloody stools?
Patients with pancreatic cancer may exhibit clinical symptoms of bloody stools, and the possible causes are as follows: First, the lesion of pancreatic cancer invades organs and tissues such as the gastrointestinal tract, causing damage to the mucous membranes, which clinically results in bloody stools. Second, if the pancreatic cancer metastasizes to the liver, liver function is impaired. Some patients may develop hyperactive splenic function, leading to a decline in platelet counts. When platelet levels drop to a certain extent, spontaneous visceral bleeding can occur, which may also manifest as bloody stools clinically. Third, in the late stages of pancreatic cancer, the disease may cause metastasis to multiple organs, leading to the complication of disseminated intravascular coagulation. This results in impaired coagulation function, making gastrointestinal bleeding likely, which is also clinically manifested as bloody stools.
Does melanoma feel painful when pressed?
Melanoma is a highly malignant skin cancer, and clinically, some patients may experience pain when pressing on the lesion area. The reason for the pain is mainly due to the rapid growth of the melanoma, leading to compression of local tissues or the optic nerve and urgency, resulting in a painful sensation. This pain can exist even without pressing, and ulcerative lesions can occur in some affected areas, leading to symptoms such as pain, bleeding, and infection. In addition to pain upon local compression, patients with melanoma may also experience inflammatory changes such as redness, swelling, heat, and pain, causing some clinical symptoms of fever.
Kidney cancer most commonly metastasizes to which locations?
Kidney cancer clinically tends to metastasize through direct spread, the lymphatic pathway, and the hematogenous pathway. The lymphatic route often involves enlargement of the perirenal lymph nodes or the lymph nodes in the groin or retroperitoneum. Kidney cancer is also prone to metastasize to the lungs, liver, bones, and other parts via the bloodstream. Similarly, kidney cancer can spread to the perirenal area, ureters, bladder, and other parts through direct extension. Once kidney cancer metastasizes to other organs, it is considered to be in the advanced stages clinically, and treatment primarily involves targeted therapy, chemotherapy, and other comprehensive treatment measures, with surgical treatment not being used as the primary anti-tumor treatment. Once kidney cancer has metastasized, the clinical staging is late, and the prognosis for the patients is poor.